ArticleJournal of human hypertension2011
Antihypertensive treatment and control in a large primary care population of 21 167 patients.
Article in Journal of human hypertension, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex Differences in Cardiovascular Medication Prescription in Primary Care: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2020Pooled it
- A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixed-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide.Journal of clinical hypertension (Greenwich, Conn.) · 2011Trial
- Sex differences in the prescription of antihypertensive medications in primary care patients: an observational study.BJGP open · 2025Article
- Observational
- Sex Differences in the Primary Prevention of Cardiovascular Diseases in a Dutch Primary Care Setting.Global heart · 2024Article
- Article
- Utilization, Cost, and Affordability of Antihypertensive Therapy in Bulgaria.Iranian journal of pharmaceutical research : IJPR · 2021Article
- Sex differences in spontaneous reports on adverse drug events for common antihypertensive drugs.European journal of clinical pharmacology · 2018Article
- Persistence to antihypertensive drug classes: A cohort study using the Swedish Primary Care Cardiovascular Database (SPCCD).Medicine · 2016Observational
- Guest Editorial Challenges in Resistant Hypertension.European cardiology · 2016Review
- Improved Blood Pressure Control Using an Interactive Mobile Phone Support System.Journal of clinical hypertension (Greenwich, Conn.) · 2016Article
- Long term trends in control of hypertension in the Northern Sweden MONICA study 1986-2009.BMC public health · 2015Article
- Antihypertensive treatment and control according to gender, education, country of birth and psychiatric disorder: the Swedish Primary Care Cardiovascular Database (SPCCD).Journal of human hypertension · 2015Article
- Persistence to antihypertensive drug treatment in Swedish primary healthcare.European journal of clinical pharmacology · 2013Article
- Multimorbidity and blood pressure control in 37 651 hypertensive patients from Danish general practice.Journal of the American Heart Association · 2012Article
- Integrated control of hypertension by olmesartan medoxomil and hydrochlorothiazide and rationale for combination.Integrated blood pressure control · 2011Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The efficacy of antihypertensive drug therapy is undisputed, but observational studies show that few patients reach a target blood pressure <140/90 mm Hg. However, there is limited data on the drug prescribing patterns and their effectiveness in real practice. This retrospective observational survey of electronic patient records extracted data from 24 Swedish primary health-care centres, with a combined registered population of 330 000 subjects. We included all patients > 30 years with a recorded diagnosis of hypertension who consulted the centres in 2005 or 2006 (n=21 167). Main outcome measures were systolic and diastolic blood pressures, and prescribed antihypertensive drug classes. Only 27% had a blood pressure <140/90 mm Hg. The number of prescribed drugs increased with age, except among the oldest (> 90 years). Only 29% of patients given monotherapy had a blood pressure <140/90 mm Hg. Women more often received diuretics (52 vs 42%), and less often angiotensin-converting enzyme inhibitors (22 vs 33%) and calcium channel blockers (26 vs 31%) than men. β-Blockers and diuretics were the most common drug classes prescribed, independent of comorbidity. In conclusion, one out of four primary care patients with hypertension reach target blood pressure. More frequent use of drug combinations may improve blood pressure control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.