ArticleProceedings. Biological sciences2011
How the insect immune system interacts with an obligate symbiotic bacterium.
Article in Proceedings. Biological sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 67 citations in OpenAlex.
- Comparative genomics reveal signatures of ecological specialization in the striped ambrosia beetle Trypodendron lineatum.BMC genomics · 2026Article
- Insect immune systems: same same but different but still same.Frontiers in immunology · 2026Review
- A novel prolixicin identified in common bed bugs with activity against both bacteria and parasites.Scientific reports · 2024Article
- How It All Begins: Bacterial Factors Mediating the Colonization of Invertebrate Hosts by Beneficial Symbionts.Microbiology and molecular biology reviews : MMBR · 2022Review
- Evolution and ontogeny of bacteriocytes in insects.Frontiers in physiology · 2022Review
- Effects of feeding on different parts ofFrontiers in microbiology · 2022Article
- Defensive Symbioses in Social Insects Can Inform Human Health and Agriculture.Frontiers in microbiology · 2020Article
- Dynamic Evolution of Antimicrobial Peptides Underscores Trade-Offs Between Immunity and Ecological Fitness.Frontiers in immunology · 2019Article
- Genome Reduction in the Mosquito Symbiont Asaia.Genome biology and evolution · 2019Article
- 16S rRNA Gene Sequencing Reveals a Shift in the Microbiota ofFrontiers in microbiology · 2019Article
- Localization and dynamics of Wolbachia infection in Asian citrus psyllid Diaphorina citri, the insect vector of the causal pathogens of Huanglongbing.MicrobiologyOpen · 2018Article
- Diaphorina citri Nymphs Are Resistant to Morphological Changes Induced by "Candidatus Liberibacter asiaticus" in Midgut Epithelial Cells.Infection and immunity · 2018Article
- Symbiotic immuno-suppression: is disease susceptibility the price of bleaching resistance?PeerJ · 2018Article
- Article
- Peptidoglycan in obligate intracellular bacteria.Molecular microbiology · 2018Review
- Genome Sequencing of the Phytoseiid Predatory Mite Metaseiulus occidentalis Reveals Completely Atomized Hox Genes and Superdynamic Intron Evolution.Genome biology and evolution · 2016Article
- Heritable symbiosis: The advantages and perils of an evolutionary rabbit hole.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Systemic infection generates a local-like immune response of the bacteriome organ in insect symbiosis.Journal of innate immunity · 2015Article
- Population dynamics and growth rates of endosymbionts during Diaphorina citri (Hemiptera, Liviidae) ontogeny.Microbial ecology · 2014Article
- Systems biology perspectives on minimal and simpler cells.Microbiology and molecular biology reviews : MMBR · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
The animal immune system provides defence against microbial infection, and the evolution of certain animal-microbial symbioses is predicted to involve adaptive changes in the host immune system to accommodate the microbial partner. For example, the reduced humoral immune system in the pea aphid Acyrthosiphon pisum, including an apparently non-functional immune deficiency (IMD) signalling pathway and absence of peptidoglycan recognition proteins (PGRPs), has been suggested to be an adaptation for the symbiosis with the bacterium Buchnera aphidicola. To investigate this hypothesis, the interaction between Buchnera and non-host cells, specifically cultured Drosophila S2 cells, was investigated. Microarray analysis of the gene expression pattern in S2 cells indicated that Buchnera triggered an immune response, including upregulated expression of genes for antimicrobial peptides via the IMD pathway with the PGRP-LC as receptor. Buchnera cells were readily taken up by S2 cells, but were subsequently eliminated over 1-2 days. These data suggest that Buchnera induces in non-host cells a defensive immune response that is deficient in its host. They support the proposed contribution of the Buchnera symbiosis to the evolution of the apparently reduced immune function in the aphid host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.