Evidence map›Paper›PMID 20717628›Full record

ArticleChemical communications (Cambridge, England)2010

A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.

Kathleen C A Garber, Kittikhun Wangkanont, Erin E Carlson, Laura L Kiessling

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 62 citations in OpenAlex.

  1. Synthetic Ligands of Myeloid C-Type Lectin Receptors.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Computational Pipeline for Accelerating the Design of Glycomimetics.Journal of chemical information and modeling · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins.Angewandte Chemie (International ed. in English) · 2021
    Article
  9. Review
  10. Antigen structure affects cellular routing through DC-SIGN.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  11. Strategies for the Development of Glycomimetic Drug Candidates.Pharmaceuticals (Basel, Switzerland) · 2019
    Review
  12. Glycopolymer probes of signal transduction.Chemical Society reviews · 2013
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kathleen C A GarberDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706, USA.
Kittikhun Wangkanont
Erin E Carlson
Laura L Kiessling
University of Wisconsin–Madison · US

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
Chemistry-Biology Interface Training ProgramT32GM008505 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLACKWELL, HELEN E. · 1993 to 2023
$9.8M
PROBES OF CARBOHYDRATE FUNCTIONR01GM049975 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KIESSLING, LAURA L · 1999 to 2016
$5.2M
NIGMS NIH HHS R01 GM049975NIGMS NIH HHS T32 GM008349NIGMS NIH HHS T32 GM008505NIGMS NIH HHS T32GM08349
6 · The paper itself

Abstract

Shikimic acid can be transformed into monovalent and multivalent glycomimetics that target different members of the C-type lectin class, including DC-SIGN, a dendritic cell lectin that facilitates HIV transmission.

Indexed as

Binding SitesCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinHIV InfectionsHumansLectins, C-TypeReceptors, Cell SurfaceShikimic AcidSmall Molecule LibrariesCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinLectins, C-TypeReceptors, Cell SurfaceShikimic AcidSmall Molecule Libraries

Identifiers

PMID20717628
PMCPMC3005762
OpenAlexW2082428599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.