ArticleLab on a chip2010
Measurement of the volume growth rate of single budding yeast with the MOSFET-based microfluidic Coulter counter.
Article in Lab on a chip, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- A single-cell identification and capture chip for automatically and rapidly determining hydraulic permeability of cells.Analytical and bioanalytical chemistry · 2020Article
- Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties.Stem cells international · 2019Article
- One-Cell Doubling Evaluation by Living Arrays of Yeast, ODELAY!G3 (Bethesda, Md.) · 2017Article
- Multi-parameter analysis using photovoltaic cell-based optofluidic cytometer.Biomedical optics express · 2016Article
- Microfluidic based high throughput synthesis of lipid-polymer hybrid nanoparticles with tunable diameters.Biomicrofluidics · 2015Article
- Quantifying the volume of single cells continuously using a microfluidic pressure-driven trap with media exchange.Biomicrofluidics · 2014Article
- Temporal behavior of capsule enlargement by Cryptococcus neoformans.Eukaryotic cell · 2013Article
- Size-based hydrodynamic rare tumor cell separation in curved microfluidic channels.Biomicrofluidics · 2013Article
- Single-cell electroporation using a multifunctional pipette.Lab on a chip · 2012Article
- Simultaneous on-chip DC dielectrophoretic cell separation and quantitative separation performance characterization.Analytical chemistry · 2012Article
- Article
- Microfluidics for cryopreservation.Biotechnology advancesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We report on measurements of the volume growth rate of ten individual budding yeast cells using a recently developed MOSFET-based microfluidic Coulter counter. The MOSFET-based microfluidic Coulter counter is very sensitive, provides signals that are immune from the baseline drift, and can work with cell culture media of complex composition. These desirable features allow us to directly measure the volume growth rate of single cells of Saccharomyces cerevisiae LYH3865 strain budding yeast in YNB culture media over a whole cell cycle. Results indicate that all budding yeast follow a sigmoid volume growth profile with reduced growth rates at the initial stage before the bud emerges and the final stage after the daughter gets mature. Analysis of the data indicates that even though all piecewise linear, Gomperitz, and Hill's function models can fit the global growth profile equally well, the data strongly support local exponential growth phenomenon. Accurate volume growth measurements are important for applications in systems biology where quantitative parameters are required for modeling and simulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.