Evidence map›Paper›PMID 20716967›Full record

ArticleCancer biology & therapy2010

Nutlin's two roads toward apoptosis.

Qi Zhang, Hua Lu

Abstract readComment
In one paragraph

Article in Cancer biology & therapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Qi ZhangDepartment of Biochemistry and Molecular Biology, IU-Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Hua Lu

Funding

The Role of Ribosomal Proteins in the P53-MDM2 PathwayR01CA095441 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI LU, HUA · 2002 to 2021
$5.1M
Role of the AMPK-MDMX-p53 pathway in cancerR01CA127724 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI LU, HUA · 2007 to 2019
$3.0M
Role of ribosomal proteins in regulating c-MycR01CA129828 · NCI · TULANE UNIVERSITY OF LOUISIANA · PI LU, HUA · 2008 to 2012
$1.5M
NCI NIH HHS CA095441NCI NIH HHS CA127724NCI NIH HHS CA129828NCI NIH HHS R01 CA095441NCI NIH HHS R01 CA127724NCI NIH HHS R01 CA129828
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisApoptosis Regulatory ProteinsCell Line, TumorDose-Response Relationship, DrugGene Expression Regulation, NeoplasticHumansImidazolesImmunoblottingMultiple MyelomaPiperazinesProtein BindingProtein TransportProto-Oncogene Proteins c-mdm2Reverse Transcriptase Polymerase Chain ReactionSignal TransductionTranscription, GeneticApoptosis Regulatory ProteinsImidazolesMDM2 protein, humannutlin 3PiperazinesProto-Oncogene Proteins c-mdm2Tumor Suppressor Protein p53

Identifiers

PMID20716967
PMCPMC3040947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.