ArticleBMC bioinformatics2010
TOPSAN: a collaborative annotation environment for structural genomics.
Article in BMC bioinformatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 19 citations in OpenAlex.
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- Exploration of databases and methods supporting drug repurposing: a comprehensive survey.Briefings in bioinformatics · 2021Review
- Funding knowledgebases: Towards a sustainable funding model for the UniProt use case.F1000Research · 2017Article
- Supporting community annotation and user collaboration in the integrated microbial genomes (IMG) system.BMC genomics · 2016Article
- The impact of structural genomics: the first quindecennial.Journal of structural and functional genomics · 2016Review
- Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications.Acta crystallographica. Section D, Biological crystallography · 2014Article
- Data management in the modern structural biology and biomedical research environment.Methods in molecular biology (Clifton, N.J.) · 2014Article
- The Protein Structure Initiative Structural Biology Knowledgebase Technology Portal: a structural biology web resource.Journal of structural and functional genomics · 2012Article
- Linking genes to diseases with a SNPedia-Gene Wiki mashup.Journal of biomedical semantics · 2012Article
- Mining the Gene Wiki for functional genomic knowledge.BMC genomics · 2011Article
- TOPSAN: a dynamic web database for structural genomics.Nucleic acids research · 2011Article
- The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.Protein science : a publication of the Protein Society · 2010Article
- The JCSG high-throughput structural biology pipeline.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010Article
- Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010Article
- Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010Article
- TOPSAN: use of a collaborative environment for annotating, analyzing and disseminating data on JCSG and PSI structures.Acta crystallographica. Section F, Structural biology and crystallization communications · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMany protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositions and are not accompanied by a peer-reviewed manuscript. Because of this they are not accessible by the standard tools of literature searches, remaining underutilized by the broad biological community.
resultsTo address this issue we have developed TOPSAN, The Open Protein Structure Annotation Network, a web-based platform that combines the openness of the wiki model with the quality control of scientific communication. TOPSAN enables research collaborations and scientific dialogue among globally distributed participants, the results of which are reviewed by experts and eventually validated by peer review. The immediate goal of TOPSAN is to harness the combined experience, knowledge, and data from such collaborations in order to enhance the impact of the astonishing number and diversity of structures being determined by structural genomics centers and high-throughput structural biology.
conclusionsTOPSAN combines features of automated annotation databases and formal, peer-reviewed scientific research literature, providing an ideal vehicle to bridge a gap between rapidly accumulating data from high-throughput technologies and a much slower pace for its analysis and integration with other, relevant research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.