Evidence map›Paper›PMID 20714814›Full record

ReviewWiener medizinische Wochenschrift (1946)2010

Cell biology of osteoimmunology.

Reinhard Gruber

Abstract readReview
PubMed Publisher
In one paragraph

Review in Wiener medizinische Wochenschrift (1946), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Mechanisms of Bone Resorption in Periodontitis.Journal of immunology research · 2015
    Review
  4. Development of an Ontology for Periodontitis.Journal of biomedical semantics · 2015
    Article
  5. Novel inflammatory pathways in periodontitis.Advances in dental research · 2014
    Review
  6. Article
  7. Review
  8. Periodontitis and bone metabolism.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Reinhard GruberDepartment of Oral Surgery, Medical University of Vienna, Vienna, Austria, reinhard.gruber@meduniwien.ac.at

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoimmunology is defined as the research area focusing on the crosstalk between the immune system and the muskoskeletal system. After nearly a decade of research, we are now beginning to understand the basic principles of this crosstalk. It seems that almost all immune cells are capable of communicating with osteoblasts, osteoclasts, and their respective progenitors - and vice versa. Diseases that fall into the category of osteoimmunology including osteoporosis, rheumatoid arthritis, and periodontal disease are of particular significance considering their implications in quality of life, their increased incidence in the population, and socioeconomic issues. To better understand the underlying pathogenesis, the main pathways of the crosstalk between the immune system and the muskoskeletal system need to be uncovered. Our current understanding has already provided the scientific basis for the development of targeted therapies. However, the challenge of future studies is to further decipher this crosstalk at cellular and molecular levels.

Indexed as

Arthritis, RheumatoidBone and BonesBone DiseasesCell CommunicationHematopoietic Stem CellsHumansImmunity, CellularOsteoblastsOsteoclastsOsteoporosisOsteoprotegerinPeriodontitisRANK LigandReceptor Activator of Nuclear Factor-kappa BT-LymphocytesOsteoprotegerinRANK LigandReceptor Activator of Nuclear Factor-kappa BTNFRSF11A protein, humanTNFSF11 protein, human

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.