Evidence map›Paper›PMID 20714789›Full record

ReviewCancer metastasis reviews2010

Cancer and metastasis: prevention and treatment by green tea.

Naghma Khan, Hasan Mukhtar

Abstract readReview
In one paragraph

Review in Cancer metastasis reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 176 citations in OpenAlex.

  1. Article
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  8. Review
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  13. Thymoquinone-Loaded SoluplusMolecules (Basel, Switzerland) · 2020
    Article
  14. Nutraceuticals and Metastasis Development.Molecules (Basel, Switzerland) · 2020
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Naghma KhanDepartment of Dermatology, University of Wisconsin, 4385, Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA.
Hasan Mukhtar
University of Wisconsin–Madison · US

Funding

The Role of JunD in Androgen-Induced Changes in Prostate Gland Redox StateP50DK065303 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI BUSHMAN, WADE A. · 2003 to 2007
$4.0M
Green Tea in Chemoprevention of Prostate CancerR01CA078809 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 1999 to 2008
$1.9M
Molecular Targets for Prevention of Prostate Cancer by Green TeaR01CA101039 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 2003 to 2007
$1.6M
Pomegranate for Chemoprevention and Chemotherapy of Prostate CancerR01CA120451 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MUKHTAR, HASAN · 2007 to 2011
$1.4M
NCI NIH HHS R01 CA078809NCI NIH HHS R01 CA 101039NCI NIH HHS R01 CA101039NCI NIH HHS R01 CA 120451NCI NIH HHS R01 CA120451NCI NIH HHS R01 CA 78809NIDDK NIH HHS P50 DK065303
6 · The paper itself

Abstract

Metastasis is the most deadly aspect of cancer and results from several interconnected processes including cell proliferation, angiogenesis, cell adhesion, migration, and invasion into the surrounding tissue. The appearance of metastases in organs distant from the primary tumor is the most destructive feature of cancer. Metastasis remains the principal cause of the deaths of cancer patients despite decades of research aimed at restricting tumor growth. Therefore, inhibition of metastasis is one of the most important issues in cancer research. Several in vitro, in vivo, and epidemiological studies have reported that the consumption of green tea may decrease cancer risk. (-)-Epigallocatechin-3-gallate, major component of green tea, has been shown to inhibit tumor invasion and angiogenesis which are essential for tumor growth and metastasis. This article summarizes the effect of green tea and its major polyphenolic compounds on cancer and metastasis against most commonly diagnosed cancer sites.

Indexed as

TeaClinical Trials as TopicHumansNeoplasm MetastasisNeoplasmsTea

Identifiers

PMID20714789
PMCPMC3142888
OpenAlexW2079670861

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.