Trial reportPsychopharmacology2010
Effects of acute modafinil on cognition in trichotillomania.
Trial report in Psychopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Pharmacotherapy for trichotillomania.The Cochrane database of systematic reviews · 2021Pooled it
- Pharmacological treatments in pathological gambling.British journal of clinical pharmacology · 2014Pooled it
- Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods.Dermatology and therapy · 2018Review
- Neurocognitive Findings in Onychophagia (Pathological Nail Biting).The Psychiatric quarterly · 2017Article
- Review of available studies of the neurobiology and pharmacotherapeutic management of trichotillomania.Journal of advanced research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
rationaleIndividuals with trichotillomania often report significant difficulty resisting the urges and drive to pull hair.
objectivesThe aim of this study is to examine whether modafinil improves motor inhibitory control, and other cognitive functions, in trichotillomania.
methodsEighteen subjects with trichotillomania (mean age 33.4 ± 12.8 years; 78% female) received a single dose of modafinil (200 mg) and placebo in a crossover double-blind design. Neurocognitive performance was assessed using the stop-signal, pattern recognition, rapid visual information processing and Tower of London tasks.
resultsNo effects of modafinil on cognition approached statistical significance on the test measures examined (all p > 0.10).
conclusionsThese results suggest that modafinil may not be useful for targeting impulse dyscontrol in trichotillomania. However, it remains possible that relatively small effects of modafinil on cognition could exert larger downstream effects on overt behaviour. Further trials using modafinil and other pro-cognitive agents are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.