Evidence map›Paper›PMID 20714299›Full record

ReviewMolecules (Basel, Switzerland)2010

Solid-phase synthesis of N-substituted glycine oligomers (alpha-peptoids) and derivatives.

Adrian S Culf, Rodney J Ouellette

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Therapeutic peptides and proteins: Status and developments in drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  2. Sequence-defined peptoidsChemical science · 2025
    Article
  3. Article
  4. Systematic Investigation on Acid-Catalyzed Truncation ofInternational journal of molecular sciences · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Minimal Peptoid Dynamics Inform Self-Assembly Propensity.The journal of physical chemistry. B · 2023
    Article
  9. A Peptoid-Chelator Selective to CuAntioxidants (Basel, Switzerland) · 2023
    Article
  10. Oxidative Degradation of Sequence-Defined Peptoid Oligomers.Molecular systems design & engineering · 2023
    Article
  11. Article
  12. First series ofBeilstein journal of organic chemistry · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Solid-Phase Insertion ofMolecules (Basel, Switzerland) · 2019
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adrian S CulfAtlantic Cancer Research Institute, Moncton, NB, Canada. adrianc@canceratl.ca
Rodney J Ouellette

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-acid monomer units) are oligomeric synthetic polymers that are becoming a valuable molecular tool in the biosciences. Of particular interest are their applications to the exploration of peptoid secondary structures and drug design. Major advantages of peptoids as research and pharmaceutical tools include the ease and economy of synthesis, highly variable backbone and side-chain chemistry possibilities. At the same time, peptoids have been demonstrated as highly active in biological systems while resistant to proteolytic decay. This review with 227 references considers the solid-phase synthetic aspects of peptoid preparation and utilization up to 2010 from the instigation, by R. N. Zuckermann et al., of peptoid chemistry in 1992.

Indexed as

Protein Structure, QuaternaryAcylationAminationN-substituted GlycinesSolventsN-substituted GlycinesSolvents

Identifiers

PMID20714299
PMCPMC6257730

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.