ArticleAutophagy2010
The Golgi complex as a source for yeast autophagosomal membranes.
Article in Autophagy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed.
- Modulation of Autophagy: A Novel "Rejuvenation" Strategy for the Aging Liver.Oxidative medicine and cellular longevity · 2021Review
- Interplay Between the Autophagy-Lysosomal Pathway and the Ubiquitin-Proteasome System: A Target for Therapeutic Development in Alzheimer's Disease.Frontiers in cellular neuroscience · 2018Review
- BNIP3L-dependent mitophagy accounts for mitochondrial clearance during 3 factors-induced somatic cell reprogramming.Autophagy · 2017Article
- SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages.Autophagy · 2017Article
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- Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway.Developmental cell · 2014Article
- Autophagic cellular responses to physical exercise in skeletal muscle.Sports medicine (Auckland, N.Z.) · 2014Review
- A quinoxaline derivative as a potent chemotherapeutic agent, alone or in combination with benznidazole, against Trypanosoma cruzi.PloS one · 2014Article
- Endosome-mediated autophagy: an unconventional MIIC-driven autophagic pathway operational in dendritic cells.Autophagy · 2013Article
- Trs130 participates in autophagy through GTPases Ypt31/32 in Saccharomyces cerevisiae.Traffic (Copenhagen, Denmark) · 2013Article
- ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner.Autophagy · 2012Article
- Autophagy in immunity: implications in etiology of autoimmune/autoinflammatory diseases.Autophagy · 2012Review
- Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons.The Journal of cell biology · 2012Article
- Autophagy: more than a nonselective pathway.International journal of cell biology · 2012Article
- Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy.Chemistry & biology · 2011Article
- Autophagy in immunity and cell-autonomous defense against intracellular microbes.Immunological reviews · 2011Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Today, more than 50 years after the discovery of autophagy, the origin of the autophagosomal membranes remains for the most part elusive. Many sources for the lipid bilayers have been proposed, but no conclusive evidence has been found to support one particular origin. The lipids do not appear to be generated at the site of autophagosome formation, the phagophore assembly site (PAS), since so far no lipid synthesizing enzyme has been found at this location. The current consensus is also that the autophagosomes do not directly bud off from a pre-existing compartment, and recent evidence in mammalian cells has revealed that the nascent autophagosome could expand through a lipid transfer mechanism from an adjacent organelle. In yeast, such an event has never been observed and data from our and other laboratories suggest that the Golgi complex could be a key player in mediating the expansion of the phagophore.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.