Trial reportHypertension (Dallas, Tex. : 1979)2010
Dietary fatty acids and the risk of hypertension in middle-aged and older women.
Trial report in Hypertension (Dallas, Tex. : 1979), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 91 citations in OpenAlex.
- Impact of fatty diets on blood pressure: A systematic review and meta-analysis.Asia Pacific journal of clinical nutrition · 2025Pooled it
- Plant-Based Diets Reduce Blood Pressure: A Systematic Review of Recent Evidence.Current hypertension reports · 2023Pooled it
- Fish, Long-Chain n-3 PUFA and Incidence of Elevated Blood Pressure: A Meta-Analysis of Prospective Cohort Studies.Nutrients · 2016Pooled it
- Pooled it
- Erythrocyte fatty acid composition is associated with the risk of hypertension in middle-aged and older women.The Journal of nutrition · 2011Trial
- Effects of Daily Saskatoon Berry Supplementation on Cardiometabolic Health, Gut Microbiota, and Short-Chain Fatty Acids in Healthy Adults.International journal of molecular sciences · 2026Article
- Inflammatory Biomarkers and Serum Fatty Acids in High-Risk Populations: A Research Protocol.International journal of sciences, basic and applied research · 2026Article
- T cell knockout attenuates HFD-induced increases in blood pressure in female and male Dahl rats.Clinical science (London, England : 1979) · 2025Article
- High Blood Pressure and Impaired Brain Health: Investigating the Neuroprotective Potential of Magnesium.International journal of molecular sciences · 2024Review
- Factors associated with diabetes mellitus and hypertension among adults in the northern rural area, Afghanistan.Nagoya journal of medical science · 2024Article
- Feasibility of the MIND+SOUL Culturally Tailored Brain Healthy Diet: A Pilot Study.American journal of lifestyle medicine · 2024Article
- Assessing the Hypertension Risk: A Deep Dive into Cereal Consumption and Cooking Methods-Insights from China.Nutrients · 2024Article
- Article
- Association of dietary fats with ischemic heart disease (IHD): a case-control study.Journal of health, population, and nutrition · 2024Review
- Association of plasma trans fatty acid concentrations with blood pressure and hypertension in U.S. adults.Frontiers in endocrinology · 2024Article
- A prospective cohort study on the association between dietary fatty acids intake and risk of hypertension incident.Scientific reports · 2023Article
- Dietary fatty acid patterns and risk of metabolic syndrome: Tehran lipid and glucose study.European journal of medical research · 2023Article
- DNA Methylation of Birthweight-Blood Pressure Genes and Changes of Blood Pressure in Response to Weight-Loss Diets in the POUNDS Lost Trial.Hypertension (Dallas, Tex. : 1979) · 2023Article
- Associations between saturated fat intake and other dietary macronutrients and incident hypertension in a prospective study of French women.European journal of nutrition · 2023Article
- Dietary Fatty Acids and Inflammation: Focus on the n-6 Series.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Dietary intake of various fats may have different effects on blood pressure. We conducted a prospective cohort study to examine the association between intake of subtype and individual fatty acids (FAs) and the risk of developing hypertension among 28 100 US women aged ≥39 years and free of cardiovascular disease and cancer. Baseline intake of FAs was assessed using semiquantitative food frequency questionnaires. Incident hypertension was identified from annual follow-up questionnaires based on self-reported physician diagnosis, medication use, and blood pressure levels. A total of 13 633 women developed incident hypertension during 12.9 years of follow-up. After adjusting for demographic, lifestyle, and other dietary factors, intake of saturated FAs, monounsaturated FAs, and trans-unsaturated FAs (trans FAs) was positively associated with the risk of hypertension. The multivariable relative risks and 95% CIs of hypertension in the highest compared with the lowest quintile of intake were 1.12 (1.05 to 1.20) for saturated FAs, 1.11 (1.04 to 1.18) for monounsaturated FAs, and 1.15 (1.08 to 1.22) for trans FAs. After additional adjustment for body mass index and history of diabetes mellitus and hypercholesterolemia, these associations were attenuated and remained statistically significant only for trans FAs (relative risk in the highest quintile: 1.08; 95% CI: 1.01 to 1.15). Intake of polyunsaturated FAs, including ω3 and ω6 polyunsaturated FAs, was not significantly associated with the risk of hypertension. In conclusion, higher intake of saturated FAs, monounsaturated FAs, and trans FAs was each associated with increased risk of hypertension among middle-aged and older women, whereas only association for trans FAs remained statistically significant after adjustment for obesity-related factors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.