Evidence map›Paper›PMID 20713913›Full record

ArticleHypertension (Dallas, Tex. : 1979)2010

Trait antagonism and the progression of arterial thickening: women with antagonistic traits have similar carotid arterial thickness as men.

Angelina R Sutin, Angelo Scuteri, Edward G Lakatta, Kirill V Tarasov, Luigi Ferrucci, Paul T Costa, David Schlessinger, Manuela Uda, Antonio Terracciano

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Personality and risk of Alzheimer's disease: new data and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2014
    Pooled it
  3. Genetics of serum BDNF: meta-analysis of the Val66Met and genome-wide association study.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2013
    Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Independent effects of early-life experience and trait aggression on cardiovascular function.American journal of physiology. Regulatory, integrative and comparative physiology · 2016
    Article
  8. Article
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  15. Article
  16. Breastfeeding and Adult Personality.European journal of personality
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Angelina R SutinNational Institute on Aging, National Institutes of Health, Department of Health and HumanServices, Baltimore, MD 21224. sutina@mail.nih.gov
Angelo Scuteri
Edward G Lakatta
Kirill V Tarasov
Luigi Ferrucci
Paul T Costa
David Schlessinger
Manuela Uda
Antonio Terracciano
Istituto Nazionale di Riposo e Cura per Anziani · IT

Funding

The Baltimore Longitudinal Study Of AgingZIAAG000015 · NIA · NATIONAL INSTITUTE ON AGING · PI SIMONSICK, ELEANOR MARIE · 2009 to 2025
$116.9M
Aging-related Traits and Disease Risk Factors in a Sardinian Population CohortZIAAG000675 · NIA · NATIONAL INSTITUTE ON AGING · PI GOROSPE, MYRIAM · 2009 to 2021
$5.7M
Basic Research In Personality: AgingZIAAG000183 · NIA · NATIONAL INSTITUTE ON AGING · PI RESNICK, SUSAN · 2009 to 2020
$2.8M
Genome-wide Association Study of Cardiovascular Traits in 6142 SardiniansZIAAG000799 · NIA · NATIONAL INSTITUTE ON AGING · PI LAKATTA, EDWARD · 2009 to 2025
$1.8M
Stress, Coping And Personality In Aging Men And WomenZIAAG000180 · NIA · NATIONAL INSTITUTE ON AGING · PI RESNICK, SUSAN · 2009 to 2012
$617k
Psychosocial Predictors of Mental and Physical Health: PsychopathologyZIAAG000197 · NIA · NATIONAL INSTITUTE ON AGING · PI RESNICK, SUSAN · 2009 to 2010
$334k
Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA AG000180Intramural NIH HHS ZIA AG000183Intramural NIH HHS ZIA AG000197
6 · The paper itself

Abstract

A large body of evidence links antagonism-related traits with cardiovascular outcomes, but less is known about how psychological traits are associated with intermediate markers of cardiovascular disease. Using a large, community-based sample from Sardinia, Italy (n=5614), this study examined how trait antagonism (low agreeableness) and its facets are associated with carotid artery intima-media thickness, a measure of arterial thickening. Controlling for demographic and cardiovascular risk factors, low agreeableness and, in particular, low straightforwardness and low compliance, were associated with greater carotid thickening, measured concurrently and prospectively, and with increases in intima-media thickness over 3 years. Indeed, those in the bottom 10% of agreeableness had a 40% increase in risk for elevated intima-media thickness. Although men have thicker arterial walls, women with antagonistic traits had similar carotid thickening as antagonistic men. Antagonistic individuals, especially those who are manipulative and aggressive, have greater increases in arterial thickening, independent of traditional cardiovascular risk factors.

Indexed as

AdolescentAdultAgedAged, 80 and overCardiovascular DiseasesCarotid ArteriesCarotid Artery DiseasesCholesterolDisease ProgressionFemaleHostilityHumansItalyLogistic ModelsMaleMiddle AgedCholesterolTriglycerides

Identifiers

PMID20713913
PMCPMC2950971
OpenAlexW2131004909

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.