ArticleAntimicrobial agents and chemotherapy2010
blaROB-1 presence on pB1000 in Haemophilus influenzae is widespread, and variable cefaclor resistance is associated with altered penicillin-binding proteins.
Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 19 citations in OpenAlex.
- Acquisition of Beta-Lactamase by Neisseria meningitidis through Possible Horizontal Gene Transfer.Antimicrobial agents and chemotherapy · 2018Article
- PCR-Based Analysis of ColE1 Plasmids in Clinical Isolates and Metagenomic Samples Reveals Their Importance as Gene Capture Platforms.Frontiers in microbiology · 2018Article
- A Naturally Occurring Single Nucleotide Polymorphism in a Multicopy Plasmid Produces a Reversible Increase in Antibiotic Resistance.Antimicrobial agents and chemotherapy · 2017Article
- Novel blaROB-1-bearing plasmid conferring resistance to β-lactams in Haemophilus parasuis isolates from healthy weaning pigs.Applied and environmental microbiology · 2015Article
- Small-plasmid-mediated antibiotic resistance is enhanced by increases in plasmid copy number and bacterial fitness.Antimicrobial agents and chemotherapy · 2015Article
- Molecular organization of small plasmids bearing blaTEM-1 and conferring resistance to β-lactams in Haemophilus influenzae.Antimicrobial agents and chemotherapy · 2012Article
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3 authors at 2 institutions in 1 country.
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Abstract
Plasmid pB1000 is a small replicon recently identified as bearing bla(ROB-1) in animal and human Pasteurellaceae in Spain. We identified pB1000 in 11 bla(ROB-1)-positive Australian and North American Haemophilus influenzae isolates, suggesting a wider role for pB1000 in disseminating bla(ROB-1). Native H. influenzae conjugative elements can mobilize plasmids similar to pB1000 at a low frequency of 10(-8), and this might account for the infrequency of bla(ROB-1) compared to the rate of occurrence of bla(TEM-1). Altered penicillin-binding protein 3 was associated with an increased cefaclor MIC in 3 isolates.
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