Evidence map›Paper›PMID 20713649›Full record

ReviewJournal of lipid research2010

Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy.

Thuc T Le, Shuhua Yue, Ji-Xin Cheng

Abstract readReview
In one paragraph

Review in Journal of lipid research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  5. Review
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  9. Review
  10. Article
  11. Application ofInternational journal of molecular sciences · 2023
    Review
  12. Article
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  19. Article
  20. Advances in stimulated Raman scattering imaging for tissues and animals.Quantitative imaging in medicine and surgery · 2021
    Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thuc T LeWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
Shuhua Yue
Ji-Xin Cheng

Funding

Multimodal multiphoton imaging of nervous system ex vivo and in vivoR01EB007243 · NIBIB · PURDUE UNIVERSITY · PI CHENG, JI-XIN · 2007 to 2009
$950k
Nonlinear Optical Imaging to Evaluate Obesity Associated Health RisksF32HL089074 · NHLBI · PURDUE UNIVERSITY · PI LE, THUC TRONG · 2007 to 2009
$148k
NHLBI NIH HHS F32 HL089074NHLBI NIH HHS F32HL089074NIBIB NIH HHS R01 EB007243NIBIB NIH HHS R01EB007243
6 · The paper itself

Abstract

Despite the ubiquitous roles of lipids in biology, the detection of lipids has relied on invasive techniques, population measurements, or nonspecific labeling. Such difficulties can be circumvented by a label-free imaging technique known as coherent anti-Stokes Raman (CARS) microscopy, which is capable of chemically selective, highly sensitive, and high-speed imaging of lipid-rich structures with submicron three-dimensional spatial resolution. We review the broad applications of CARS microscopy to studies of lipid biology in cell cultures, tissue biopsies, and model organisms. Recent technical advances, limitations of the technique, and perspectives are discussed.

Indexed as

Lipid MetabolismAnimalsDiseaseHumansMicroscopySpectrum Analysis, Raman

Identifiers

PMID20713649
PMCPMC2952550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.