Evidence map›Paper›PMID 2071364›Full record

ArticleItalian journal of neurological sciences1991

Increased acetylcholine sensitivity in Duchenne muscular dystrophy myotubes.

G Meola, E Mancinelli, L Geremia, G Scarlato

Abstract read
PubMed Publisher
In one paragraph

Article in Italian journal of neurological sciences, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hereditary human myopathies in muscle culture.Italian journal of neurological sciences · 1991
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G MeolaIstituto di Clinica Neurologica, Centro Dino Ferrari, Università degli Studi di Milano.
E Mancinelli
L Geremia
G Scarlato

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monolayer cultures were established from explants of muscle obtained from 6 patients with Duchenne muscular dystrophy (DMD) and 9 controls. Electrophysiological studies were made after 3-4 weeks in vitro, when many myotubes had formed. An intracellular electrode was used to record cell membrane potential, and acetylcholine was applied by ionophoresis. The myotubes grown from Duchenne muscle showed greater acetylcholine sensitivity than controls.

Indexed as

AcetylcholineAdolescentCells, CulturedChildChild, PreschoolElectrodesHumansIonsMembrane PotentialsMusclesMuscular DystrophiesAcetylcholineIons

Identifiers

PMID2071364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.