How is the heart rate regulated in the sinoatrial node? Another piece to the puzzle.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Compartmentalized cAMP signalling and control of cardiac rhythm.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
   Review
2. Sinus node dysfunction: current understanding and future directions.American journal of physiology. Heart and circulatory physiology · 2023
   Review
3. Recombinant Adeno-Associated Viral Vector-Mediated Gene Transfer ofInternational journal of molecular sciences · 2022
   Article
4. Structural and Electrical Remodeling of the Sinoatrial Node in Diabetes: New Dimensions and Perspectives.Frontiers in endocrinology · 2022
   Review
5. Identification of novel pulmonary vein nodes as generators of ectopic arrhythmic foci for atrial fibrillation: an immunohistochemical proof.Surgical and radiologic anatomy : SRA · 2022
   Article
6. Bidirectional flow of the funny current (IProceedings of the National Academy of Sciences of the United States of America · 2021
   Article
7. Pharmacodynamics and Pharmacokinetics of Injectable Pimobendan and Its Metabolite, O-Desmethyl-Pimobendan, in Healthy Dogs.Frontiers in veterinary science · 2021
   Article
8. Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice.PloS one · 2020
   Article
9. Neurohumoral Control of Sinoatrial Node Activity and Heart Rate: Insight From Experimental Models and Findings From Humans.Frontiers in physiology · 2020
   Review
10. How Heart Rate Should Be Controlled in Patients with Atherosclerosis and Heart Failure.Current atherosclerosis reports · 2018
    Review
11. Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes.Journal of cardiovascular development and disease · 2018
    Review
12. Modulation of cyclic nucleotide-mediated cellular signaling and gene expression using photoactivated adenylyl cyclase as an optogenetic tool.Scientific reports · 2017
    Article
13. Culture and adenoviral infection of sinoatrial node myocytes from adult mice.American journal of physiology. Heart and circulatory physiology · 2015
    Article
14. New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway.Frontiers in pharmacology · 2015
    Review
15. BK channels regulate sinoatrial node firing rate and cardiac pacing in vivo.American journal of physiology. Heart and circulatory physiology · 2014
    Article

Corrections and comments

• Comment on
  Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node.2010

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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