Evidence map›Paper›PMID 20713262›Full record

ReviewOral and maxillofacial surgery clinics of North America2010

Genetic and transcriptional control of bone formation.

Amjad Javed, Haiyan Chen, Farah Y Ghori

Open access · greenAbstract readReview
In one paragraph

Review in Oral and maxillofacial surgery clinics of North America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 140 citations in OpenAlex.

  1. Article
  2. Review
  3. Recapitulation ofJournal of orthopaedic translation · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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  18. Regulation of osteoclast-mediated bone resorption by microRNA.Cellular and molecular life sciences : CMLS · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amjad JavedDepartment of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama at Birmingham, Birmingham, AL 35294-0007, USA. javeda@uab.edu
Haiyan Chen
Farah Y Ghori
University of Alabama at Birmingham · US

Funding

Runx2 Controlled Adipocytic Differentiation in Aging MusculoskeletonR01AG030228 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAVED, AMJAD · 2006 to 2009
$952k
NIA NIH HHS R01 AG030228
6 · The paper itself

Abstract

An exquisite interplay of developmental cues, transcription factors, and coregulatory and signaling proteins support formation of skeletal elements of the jaw during embryogenesis and dynamic remodeling of alveolar bone in postnatal life. These molecules promote initial condensation of the mesenchyme, commitment of the mesenchymal progenitor to osteogenic lineage cells, and differentiation of committed osteoblasts to mature osteocytes within mineralized bone. Parallel regulatory networks promote formation of the functional osteoclast from mononuclear cells to support continuous bone remodeling within the alveolar bone. With an ever expanding list of new regulatory factors, the complexities of the molecular mechanisms that control gene expression in skeletal cells are being further appreciated. This article examines the multifunctional roles of prominent nuclear proteins, cytokines, hormones, and paracrine factors that control osteogenesis.

Indexed as

Alveolar ProcessBone DevelopmentBone RemodelingCell DifferentiationCell LineageHumansMesenchymal Stem CellsOsteoblastsOsteoclastsOsteogenesisSignal TransductionTranscription FactorsTranscription, GeneticTranscription Factors

Identifiers

PMID20713262
PMCPMC2923651
OpenAlexW2117883524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.