ArticleJournal of bone and mineral metabolism2011
Do musculoskeletal degenerative diseases affect mortality and cause of death after 10 years in Japan?
Article in Journal of bone and mineral metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Mortality risk in osteoarthritis patients: a meta-analysis of observational studies.BMC musculoskeletal disorders · 2025Pooled it
- Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data.Aging clinical and experimental research · 2021Pooled it
- Osteoarthritis and the risk of cardiovascular disease: a meta-analysis of observational studies.Scientific reports · 2016Pooled it
- Osteoarthritis and all-cause mortality in worldwide populations: grading the evidence from a meta-analysis.Scientific reports · 2016Pooled it
- Exploring the impact of integrated polyvagal exercises and knee reinforcement in females with grade II knee osteoarthritis: a randomized controlled trial.Scientific reports · 2023Trial
- Association Between Bone Ultrasonometry and Cardiovascular Morbimortality: A Systematic Review and Meta-analysis.Journal of the Endocrine Society · 2025Review
- Risk of all-cause mortality in patients with knee osteoarthritis: A systematic review and meta-analysis of cohort studies.Osteoarthritis and cartilage open · 2025Review
- Article
- Association between osteoarthritis and cardiovascular disease in elderly in Japan: an administrative claims database analysis.BMJ open · 2024Article
- Modified single-incision MIS-TLIF with expandable tubular assistance for degenerative lumbar spine diseases.Frontiers in surgery · 2024Article
- Knee Osteoarthritis, Potential Mediators, and Risk of All-Cause Mortality: Data From the Osteoarthritis Initiative.Arthritis care & research · 2021Observational
- Risk of venous thromboembolism in knee, hip and hand osteoarthritis: a general population-based cohort study.Annals of the rheumatic diseases · 2020Article
- Association of Heel Bone Mineral Density With Incident Disability and Mortality in Community-Dwelling Older Adults.JBMR plus · 2020Article
- Impact of pelvic incidence on lumbar osteophyte formation and disc degeneration in middle-aged and elderly people in a prospective cross-sectional cohort.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Article
- High tibial osteotomy solely for the purpose of return to lifelong sporting activities among elderly patients: A case series study.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2020Article
- Does symptomatic knee osteoarthritis increase the risk of all-cause mortality? Data from four international population-based longitudinal surveys of aging.Clinical rheumatology · 2019Article
- The impact of painful knee osteoarthritis on mortality: a community-based cohort study with over 24 years of follow-up.Osteoarthritis and cartilage · 2019Article
- Osteoarthritis and risk of mortality in the USA: a population-based cohort study.International journal of epidemiology · 2018Article
- ＜Editors' Choice＞ Ultrasound measurement of thigh muscle thickness for assessment of sarcopenia.Nagoya journal of medical science · 2018Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are several reports from Europe and the United States on mortality from musculoskeletal degenerative diseases; however, no reports have been published from Japan. This study is the first that has examined whether musculoskeletal degenerative diseases affect life prognosis in Japan. As many as 944 persons who were 60 years of age and older and who underwent one or more musculoskeletal checkups (knee, lower back, and bone mineral density examination) were enrolled. Survival and death after 10 years were examined. For each knee, lower back, and bone mineral density examination, subjects were divided into normal and abnormal groups. For each of the examinations (knee, lower back, or bone mineral density), 10-year mortality was compared between the two groups. Also, causes of death were examined after 10 years. As many as 805 subjects survived and 125 died. For those with and without osteoarthritis of the knee, mortality after 10 years was 17 and 10%, respectively. For those with and without lower back abnormalities, mortality after 10 years was 12 and 14%, respectively. For those with or without low bone mineral density, mortality after 10 years was 17 and 10%, respectively. Multivariate analysis adjusted for age, gender, body mass index, and lifestyle revealed that odds ratio of death after 10 years was 2.32 and 2.33 in the presence of osteoarthritis of the knee and a low bone mineral density, respectively, and thus the risk of death after 10 years was significantly high. With regard to the cause of death, cerebrovascular and cardiovascular diseases were most frequently evident in patients with osteoarthritis of the knee. Musculoskeletal degenerative diseases influence mortality after 10 years.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.