ArticlePloS one2010
A genome-wide gene function prediction resource for Drosophila melanogaster.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- NewG3 (Bethesda, Md.) · 2019Article
- deepNF: deep network fusion for protein function prediction.Bioinformatics (Oxford, England) · 2018Article
- Machine Learning Analysis IdentifiesG3 (Bethesda, Md.) · 2017Article
- Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach.BMC genomics · 2015Article
- Implications of Big Data for cell biology.Molecular biology of the cell · 2015Article
- Inferring gene ontologies from pairwise similarity data.Bioinformatics (Oxford, England) · 2014Article
- Matrix factorization-based data fusion for gene function prediction in baker's yeast and slime mold.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2014Article
- Prediction of Drosophila melanogaster gene function using Support Vector Machines.BioData mining · 2013Article
- Bottlenecks caused by software gaps in miRNA and RNAi research.Pharmaceutical research · 2012Article
- FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update.Nucleic acids research · 2012Article
- PILGRM: an interactive data-driven discovery platform for expert biologists.Nucleic acids research · 2011Article
- Signalogs: orthology-based identification of novel signaling pathway components in three metazoans.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Predicting gene functions by integrating large-scale biological data remains a challenge for systems biology. Here we present a resource for Drosophila melanogaster gene function predictions. We trained function-specific classifiers to optimize the influence of different biological datasets for each functional category. Our model predicted GO terms and KEGG pathway memberships for Drosophila melanogaster genes with high accuracy, as affirmed by cross-validation, supporting literature evidence, and large-scale RNAi screens. The resulting resource of prioritized associations between Drosophila genes and their potential functions offers a guide for experimental investigations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.