ArticleJournal of bacteriology2010
Small genes under sporulation control in the Bacillus subtilis genome.
Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed.
- To Sporulate or Not to Sporulate: Developmental Checkpoints MonitoringAnnual review of microbiology · 2025Review
- Popcorn: prediction of short coding and noncoding genomic sequences in prokaryotes.Bioinformatics (Oxford, England) · 2025Article
- Large Roles of Small Proteins.Annual review of microbiology · 2024Review
- A catalog of small proteins from the global microbiome.Nature communications · 2024Article
- Small proteins in Gram-positive bacteria.FEMS microbiology reviews · 2023Article
- A network of small RNAs regulates sporulation initiation in Clostridioides difficile.The EMBO journal · 2023Article
- Application of a Bacillus subtilis Whole-Cell Biosensor (PMethods in molecular biology (Clifton, N.J.) · 2023Article
- A Sporulation-Specific sRNA Bvs196 Contributing to the Developing Spore inMicroorganisms · 2022Article
- The Heterocyst-Specific Small RNA NsiR1 Regulates the Commitment to Differentiation in Nostoc.Microbiology spectrum · 2022Article
- Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogenRNA biology · 2021Article
- The Complex Transcriptional Landscape of Magnetosome Gene Clusters in Magnetospirillum gryphiswaldense.mSystems · 2021Article
- A new role for SR1 from Bacillus subtilis: regulation of sporulation by inhibition of kinA translation.Nucleic acids research · 2021Article
- A circadian clock in a nonphotosynthetic prokaryote.Science advances · 2021Article
- Bioluminescence dynamics in single germinating bacterial spores reveal metabolic heterogeneity.Journal of the Royal Society, Interface · 2020Article
- BceAB-Type Antibiotic Resistance Transporters Appear To Act by Target Protection of Cell Wall Synthesis.Antimicrobial agents and chemotherapy · 2020Article
- Intermolecular Communication inFrontiers in molecular biosciences · 2020Review
- Extracytoplasmic Function σ Factors Can Be Implemented as Robust Heterologous Genetic Switches in Bacillus subtilis.iScience · 2019Article
- Engineering orthogonal synthetic timer circuits based on extracytoplasmic function σ factors.Nucleic acids research · 2018Article
- Bacterial Small RNAs in Mixed Regulatory Networks.Microbiology spectrum · 2018Review
- Structural and Functional Insights into Bacillus subtilis Sigma Factor Inhibitor, CsfB.Structure (London, England : 1993) · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Using an oligonucleotide microarray, we searched for previously unrecognized transcription units in intergenic regions in the genome of Bacillus subtilis, with an emphasis on identifying small genes activated during spore formation. Nineteen transcription units were identified, 11 of which were shown to depend on one or more sporulation-regulatory proteins for their expression. A high proportion of the transcription units contained small, functional open reading frames (ORFs). One such newly identified ORF is a member of a family of six structurally similar genes that are transcribed under the control of sporulation transcription factor σ(E) or σ(K). A multiple mutant lacking all six genes was found to sporulate with slightly higher efficiency than the wild type, suggesting that under standard laboratory conditions the expression of these genes imposes a small cost on the production of heat-resistant spores. Finally, three of the transcription units specified small, noncoding RNAs; one of these was under the control of the sporulation transcription factor σ(E), and another was under the control of the motility sigma factor σ(D).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.