ReviewAgeing research reviews2011
Contemporary human genetic strategies in aging research.
Review in Ageing research reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Influence of H19 polymorphisms on breast cancer: risk assessment and prognostic implications via LincRNA H19/miR-675 and downstream pathways.Frontiers in oncology · 2024Article
- High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity.GeroScience · 2023Article
- Chinese liquor extract attenuates oxidative damage in HepG2 cells and extends lifespan ofFood science & nutrition · 2020Article
- Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart-related traits.Aging cell · 2017Article
- Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Article
- Unraveling genetic origin of aging-related traits: evolving concepts.Rejuvenation research · 2013Review
- Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children.The journals of gerontology. Series A, Biological sciences and medical sciences · 2013Article
- Genomics of human health and aging.Age (Dordrecht, Netherlands) · 2013Article
- Genes against aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012Review
- Genetic signatures of exceptional longevity in humans.PloS one · 2012Article
- Whole genome sequences of a male and female supercentenarian, ages greater than 114 years.Frontiers in genetics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Human aging is a complex, multifactorial process influenced by a number of genetic and non-genetic factors. This article first reviews genetic strategies for human aging research and considers the advantages and disadvantages of each. We then discuss the issue of phenotypic definition for genetic studies of aging, including longevity/life span, as well as disease-free survival and other endophenotypes. Finally, we argue that extensions of this area of research, including incorporation of gene×environment interactions, multivariate phenotypes, integration of functional genomic annotations, and exploitation of orthology - many of which are already initiated and ongoing - are critical to advancing this field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.