Evidence map›Paper›PMID 20709210›Full record

ReviewSeminars in oncology2010

Epidemiological and clinical studies of nutrition.

Todd M Gibson, Leah M Ferrucci, Joseph A Tangrea, Arthur Schatzkin

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Epidemiology of Prostate Cancer.World journal of oncology · 2019
    Review
  15. Article
  16. Article
  17. ImprovingJournal of oncology · 2017
    Review
  18. Diet, nutrition, and cancer: past, present and future.Nature reviews. Clinical oncology · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Todd M GibsonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA. gibsontm@mail.nih.gov
Leah M Ferrucci
Joseph A Tangrea
Arthur Schatzkin
National Institutes of Health · USNational Cancer Institute · USYale University · US

Funding

Yale/NCI Cooperative Training Program in Cancer EpidemiologyTU2CA105666 · NCI · YALE UNIVERSITY · PI MAYNE, SUSAN T · 2003 to 2007
$882k
Intramural NIH HHS Z99 CA999999NCI NIH HHS TU2-CA-105666
6 · The paper itself

Abstract

In this review, we briefly summarize some of the key developments in nutritional epidemiology and cancer over the past two decades with a focus on the strengths and limitations of study designs and dietary assessment methods. We present the evidence on dietary fat, meat, fiber, antioxidant nutrients, and calcium in relation to carcinogenesis from large cohort studies and randomized clinical trials (RCTs) and refer to the conclusions of the 2007 World Cancer Research Fund/American Institute for Cancer Research summary report. One prominent theme that emerged is the lack of concordance of results from RCTs and observational studies. There are multiple potential reasons for these discrepancies, including differences in study population, dose and timing of the exposure, adherence to an intervention, length of follow-up, and the primary endpoint. Therefore, null findings of RCTs do not necessarily indicate a lack of effect for the tested dietary factors on cancer risk, as some of these nutrients may have chemopreventive effects if given at the right time and in the right dose. It is likely that potential benefits from diet are due to a combination of food constituents rather than single components acting in isolation. Future efforts need to recognize the integrative nature of dietary exposures and attempt to study nutrients in the larger context of the foods and diets in which they are consumed.

Indexed as

DietAntioxidantsCalcium, DietaryDietary FatsDietary FiberFunctional FoodMeatNeoplasmsAntioxidantsCalcium, DietaryDietary FatsDietary Fiber

Identifiers

PMID20709210
PMCPMC2921609
OpenAlexW2020703311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.