ArticleJournal of nanobiotechnology2010
Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system.
Article in Journal of nanobiotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Natural Compound-Loaded PLGA Nanocarriers for Infected Wound Management: A Review.International journal of nanomedicine · 2026Review
- Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation.Small science · 2026Review
- Microfluidics Technology for the Design and Formulation of Nanomedicines.Nanomaterials (Basel, Switzerland) · 2021Review
- Microfluidic Synthesis of Indomethacin-Loaded PLGA Microparticles Optimized by Machine Learning.Frontiers in molecular biosciences · 2021Article
- Regulation of the Ocular Cell/Tissue Response by Implantable Biomaterials and Drug Delivery Systems.Bioengineering (Basel, Switzerland) · 2020Review
- Theranostic Designed Near-Infrared Fluorescent Poly (Lactic-co-Glycolic Acid) Nanoparticles and Preliminary Studies with Functionalized VEGF-Nanoparticles.Journal of clinical medicine · 2020Article
- Microfluidics-Assisted Size Tuning and Biological Evaluation of PLGA Particles.Pharmaceutics · 2019Article
- Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review.Interventional medicine & applied science · 2019Review
- Size-controlled fabrication of zein nano/microparticles by modified anti-solvent precipitation with/without sodium caseinate.International journal of nanomedicine · 2017Article
- Targeted concurrent and sequential delivery of chemotherapeutic and antiangiogenic agents to the brain by using drug-loaded nanofibrous membranes.International journal of nanomedicine · 2017Article
- Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies?Regenerative biomaterials · 2016Review
- Semi-automated nanoprecipitation-system--an option for operator independent, scalable and size adjustable nanoparticle synthesis.Pharmaceutical research · 2015Article
- Development and optimization of quercetin-loaded PLGA nanoparticles by experimental design.Clujul medical (1957) · 2015Article
- Article
- Particles from preformed polymers as carriers for drug delivery.EXCLI journal · 2014Review
- Hydroxyapatite-Based Colloidal Gels Facilitate the Proliferation and Migration of Chondrocytes and the Adhesion of Umbilical Cord Mesenchymal Stem Cells.International scholarly research notices · 2014Article
- Integrative nanomedicine: treating cancer with nanoscale natural products.Global advances in health and medicine · 2014Review
- One-step fabrication of polymeric Janus nanoparticles for drug delivery.Langmuir : the ACS journal of surfaces and colloids · 2012Article
- Development and validation of an RP-HPLC method for CB13 evaluation in several PLGA nanoparticle systems.TheScientificWorldJournal · 2012Article
- Fabrication and optimization of camptothecin loaded Eudragit S 100 nanoparticles by Taguchi L4 orthogonal array design.International journal of pharmaceutical investigationArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Particle size is a key feature in determining performance of nanoparticles as drug carriers because it influences circulating half-life, cellular uptake and biodistribution. Because the size of particles has such a major impact on their performance, the uniformity of the particle population is also a significant factor. Particles comprised of the polymer poly(lactic-co-glycolic acid) (PLGA) are widely studied as therapeutic delivery vehicles because they are biodegradable and biocompatible. In fact, microparticles comprised of PLGA are already approved for drug delivery. Unfortunately, PLGA nanoparticles prepared by conventional methods usually lack uniformity. We developed a novel Fluidic NanoPrecipitation System (FNPS) to fabricate highly uniform PLGA particles. Several parameters can be fine-tuned to generate particles of various sizes.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.