Evidence map›Paper›PMID 20706806›Full record

ReviewCurrent gastroenterology reports2010

Sampling of the intestinal microbiota by epithelial M cells.

Joseph M Pickard, Alexander V Chervonsky

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Germinal center responses at barrier organ sites.Current opinion in immunology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mammalian gut immunity.Biomedical journal
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph M PickardDepartment of Pathology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA.
Alexander V Chervonsky

Funding

B Cells and Development of Intestinal EpitheliumR01AI052210 · NIAID · UNIVERSITY OF CHICAGO · PI CHERVONSKY, ALEXANDER V · 2002 to 2005
$1.3M
NIAID NIH HHS R01 AI052210
6 · The paper itself

Abstract

Sampling of intestinal pathogens and commensals is an important aspect of the gut immune system, and is accomplished through the action of specialized epithelial M cells. Although their sampling abilities have been appreciated for decades, few molecular details of their development or function are known. This review discusses several recent advances in our understanding of these cells, including signals controlling their development, the mechanisms they use for taking up microbes, and their exploitation by certain pathogens. Future research directions are discussed, including development of oral vaccines.

Indexed as

AnimalsAntigens, BacterialEpithelial CellsGene ExpressionHomeostasisHumansIntestinal MucosaIntestinesMicePeyer's PatchesVaccinationAntigens, Bacterial

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.