Evidence map›Paper›PMID 20706686›Full record

ArticleInternational journal of pediatrics2010

Exercise stress testing in children with metabolic or neuromuscular disorders.

Tim Takken, Wim G Groen, Erik H Hulzebos, Cornelia G Ernsting, Peter M van Hasselt, Berthil H Prinsen, Paul J Helders, Gepke Visser

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03326622 (The Role of Moderate Aerobic Exercise as Determined by Cardiopulmonary Exercise Testing in ALS), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03326622 nacompletednot on this mapstarted 2013, after this paper: background citation

The Role of Moderate Aerobic Exercise as Determined by Cardiopulmonary Exercise Testing in ALS

TypeinterventionalSponsorUniversity of LisbonRan2013 to 2015Enrolled48ConditionsAmyotrophic Lateral SclerosisArmsstandard care, moderate exercise
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tim TakkenChild Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The Netherlands.
Wim G Groen
Erik H Hulzebos
Cornelia G Ernsting
Peter M van Hasselt
Berthil H Prinsen
Paul J Helders
Gepke Visser
Wilhelmina Children's Hospital · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.

Identifiers

PMID20706686
PMCPMC2913792
OpenAlexW2154392126

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.