ArticleInterdisciplinary perspectives on infectious diseases2010
Global distribution, public health and clinical impact of the protozoan pathogen cryptosporidium.
Article in Interdisciplinary perspectives on infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 7 syntheses or guidelines pooled it, 208 citations in OpenAlex.
- Prevalence, Genetic Diversity, and Zoonotic Transmission Potential of Cryptosporidium spp. in Snakes: A Systematic Review and Meta-Analysis.Veterinary medicine and science · 2026Pooled it
- Cryptosporidium in Rabbits: A Global Systematic Review and Meta-Analysis of Prevalence, Species/Genotypes Distribution and Zoonotic Significance.Veterinary medicine and science · 2025Pooled it
- A retrospective epidemiological analysis of human Cryptosporidium infection in China during the past three decades (1987-2018).PLoS neglected tropical diseases · 2020Pooled it
- Anthroponotic transmission of Cryptosporidium parvum predominates in countries with poorer sanitation: a systematic review and meta-analysis.Parasites & vectors · 2019Pooled it
- A review of wildlife tourism and meta-analysis of parasitism in Africa's national parks and game reserves.Parasitology research · 2018Pooled it
- Risk factors for Cryptosporidium infection in low and middle income countries: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- Human cryptosporidiosis in Iran: a systematic review and meta-analysis.Parasitology research · 2017Pooled it
- Examination of ELISA against PCR for assessing treatment efficacy against Cryptosporidium in a clinical trial context.PloS one · 2023Trial
- Genetic Diversity of Cryptosporidium in Children in an Urban Informal Settlement of Nairobi, Kenya.PloS one · 2015Trial
- Review
- Fish and shellfish as sentinels of aquatic contamination: Global distribution and One Health implications of zoonoticOne health (Amsterdam, Netherlands) · 2026Review
- Long non-coding RNA U90926 modulates IFN-γ-stimulated gene transcription and cell-intrinsic anti-Infection and immunity · 2025Article
- Article
- Oral Treatment of Lactoferrin Nanocapsules Modulates the Immune Response of Mice to a Cryptosporidiosis Infection.Acta parasitologica · 2025Article
- Implementation of real-time PCR assays for diagnosing intestinal protozoa infections.Parasitology research · 2025Article
- The "Doorstop Pocket" In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery.Journal of medicinal chemistry · 2024Review
- Intestinal parasitic infections in children from marginalised Roma communities: prevalence and risk factors.BMC infectious diseases · 2024Article
- Article
- Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth.Cell reports · 2023Article
- Infectious Disease Sensitivity to Climate and Other Driver-Pressure Changes: Research Effort and Gaps for Lyme Disease and Cryptosporidiosis.GeoHealth · 2023Review
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cryptosporidium spp. are coccidians, oocysts-forming apicomplexan protozoa, which complete their life cycle both in humans and animals, through zoonotic and anthroponotic transmission, causing cryptosporidiosis. The global burden of this disease is still underascertained, due to a conundrum transmission modality, only partially unveiled, and on a plethora of detection systems still inadequate or only partially applied for worldwide surveillance. In children, cryptosporidiosis encumber is even less recorded and often misidentified due to physiological reasons such as early-age unpaired immunological response. Furthermore, malnutrition in underdeveloped countries or clinical underestimation of protozoan etiology in developed countries contribute to the underestimation of the worldwide burden. Principal key indicators of the parasite distribution were associated to environmental (e.g., geographic and temporal clusters, etc.) and host determinants of the infection (e.g., age, immunological status, travels, community behaviours). The distribution was geographically mapped to provide an updated picture of the global parasite ecosystems. The present paper aims to provide, by a critical analysis of existing literature, a link between observational epidemiological records and new insights on public health, and diagnostic and clinical impact of cryptosporidiosis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.