Evidence map›Paper›PMID 20705402›Full record

SynthesisDrug and alcohol dependence2010

A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization.

Marwan M Azar, Sandra A Springer, Jaimie P Meyer, Frederick L Altice

4 registry-linked trialsAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Drug and alcohol dependence, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 280 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
280citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01671501 nacompletednot on this mapstarted 2013, after this paper: background citation

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

TypeinterventionalSponsorUniversity of California, San FranciscoRan2013 to 2017Enrolled614ConditionsHIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic IntoxicationArmsMotivational Interviewing, Email Feedback, Usual Care
NCT02356185 unknown statusnot on this mapstarted 2015, after this paper: background citation

Prevalence, Socio-demographic Correlates of Substance Use Disorders Among HIV-infected Adults in Cameroon, and Their Influence on Adherence to Antiretroviral Therapy and Immunological Feature: Study Protocol for a Retrospective Cohort Study

TypeobservationalSponsorGoulfey Health District UnitRan2015 to 2015Enrolled1,000ConditionsHIV
NCT04054466 nacompletednot on this mapstarted 2018, after this paper: background citation

Effectiveness of the Nursing Counseling to the Change of Behavior of Alcohol Consumption in Patients Receiving HAART

TypeinterventionalSponsorUniversidad Peruana Cayetano HerediaRan2018 to 2020Enrolled233ConditionsHIV, Alcohol DrinkingArmsNursing Counseling in the change of Alcohol Consumption Behavior in patients receiving HAART, Habitual Counseling
NCT04601064 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Peer Supported Collaborative Care to Increase Engagement in Mental Health and Substance Use Disorder Care in HIV Care Settings

TypeinterventionalSponsorJohns Hopkins UniversityRan2022 to 2026Enrolled405ConditionsHIV Infections, Substance Use Disorders, Mental Health Disorder, AddictionArmsCollaborative Care Model
3 · Its place in the literature

Who cites it

280 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  10. Integrating HIV and substance use services: a systematic review.Journal of the International AIDS Society · 2017
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220 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marwan M AzarYale University School of Medicine, Department of Medicine, Section of Infectious Diseases, AIDS Program, 135 College Street, Suite 323, New Haven 06511, CT, USA.
Sandra A Springer
Jaimie P Meyer
Frederick L Altice

Funding

INTERDISCIPLINARY HIV PREVENTION TRAINING PROGRAMT32MH020031 · NIMH · YALE UNIVERSITY · PI Trace S Kershaw · 1999 to 2026
$12.1M
TRAINING IN THE PATHOGENESIS OF INFECTIOUS DISEASEST32AI007517 · NIAID · YALE UNIVERSITY · PI Jaimie Meyer, Albert C Shaw · 1997 to 2026
$6.1M
Alcohol Pharmacotherapies Among Released PrisonersR01AA018944 · NIAAA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS, SPRINGER, SANDRA ANN · 2009 to 2013
$3.8M
Direct/Observed Therapy/Community-Released HIV+PrisonersR01DA017059 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2004 to 2008
$3.3M
Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
Opiate Dependence, HIV and Adherence InterventionsK23DA019381 · NIDA · YALE UNIVERSITY · PI SPRINGER, SANDRA ANN · 2005 to 2009
$874k
NIAAA NIH HHS R01 AA018944NIAID NIH HHS T32 AI007517NIAID NIH HHS T32-AI007517-10NIDA NIH HHS K23 DA019381NIDA NIH HHS K24 DA017072NIDA NIH HHS R01 DA017059NIMH NIH HHS T32 MH020031
6 · The paper itself

Abstract

backgroundAlcohol use disorders (AUDs) are highly prevalent and associated with non-adherence to antiretroviral therapy, decreased health care utilization and poor HIV treatment outcomes among HIV-infected individuals.

objectivesTo systematically review studies assessing the impact of AUDs on: (1) medication adherence, (2) health care utilization and (3) biological treatment outcomes among people living with HIV/AIDS (PLWHA). DATA SOURCES: Six electronic databases and Google Scholar were queried for articles published in English, French and Spanish from 1988 to 2010. Selected references from primary articles were also examined. REVIEW

methodsSelection criteria included: (1) AUD and adherence (N=20); (2) AUD and health services utilization (N=11); or (3) AUD with CD4 count or HIV-1 RNA treatment outcomes (N=10). Reviews, animal studies, non-peer reviewed documents and ongoing studies with unpublished data were excluded. Studies that did not differentiate HIV+ from HIV- status and those that did not distinguish between drug and alcohol use were also excluded. Data were extracted, appraised and summarized. DATA SYNTHESIS AND

conclusionsOur findings consistently support an association between AUDs and decreased adherence to antiretroviral therapy and poor HIV treatment outcomes among HIV-infected individuals. Their effect on health care utilization, however, was variable.

Indexed as

Antiretroviral Therapy, Highly ActiveMedication AdherenceAlcohol DrinkingAlcohol-Related DisordersAnti-HIV AgentsCD4 Lymphocyte CountClinical Trials as TopicDelivery of Health CareHIV-1HIV InfectionsHIV SeropositivityHumansTreatment OutcomeViral LoadAnti-HIV Agents

Identifiers

PMID20705402
PMCPMC2997193

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.