Evidence map›Paper›PMID 20705235›Full record

ArticleMolecular cell2010

A novel effector protein modulates response regulator activity without altering phosphorylation.

Patrick D Curtis, Yves V Brun

Abstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Patrick D CurtisDepartment of Biology, Indiana University, Bloomington, IN 47405, USA.
Yves V Brun

Funding

GLOBAL CONTROL OF DIFFERENTIATION IN CAULOBACTERR01GM051986 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BRUN, YVES V · 1995 to 2016
$6.0M
PodJ processing and polar development in Caulobacter crescentusF32GM084618 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CURTIS, PATRICK DAVID · 2008 to 2010
$143k
NIGMS NIH HHS F32 GM084618NIGMS NIH HHS R01 GM051986
6 · The paper itself

Abstract

Genes positively regulated by the global transcriptional response regulator CtrA are not expressed during a life cycle stage of Caulobacter crescentus when the regulator is activated by phosphorylation. Gora et al. (2010), in this issue of Molecular Cell, have discovered a novel effector protein that prevents activation but not repression by the regulator without altering its phosphorylation.

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.