ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2011
A gene encoding an abscisic acid biosynthetic enzyme (LsNCED4) collocates with the high temperature germination locus Htg6.1 in lettuce (Lactuca sp.).
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 64 citations in OpenAlex.
- Genome-wide association studies in lettuce reveal the interplay of seed age, color, and germination under high temperatures.Scientific reports · 2025Article
- QTL mapping and transcriptome analysis of seed germination under PEG-induced water stress in Lactuca spp.Scientific reports · 2024Article
- Seed color in lettuce is determined by the LsTT2, LsCHS, and Ls2OGD genes from the flavonoid biosynthesis pathway.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Review
- ABA Metabolism and Homeostasis in Seed Dormancy and Germination.International journal of molecular sciences · 2021Review
- Divergent Selection for Seed Ability to Germinate at Extreme Temperatures in Perennial Ryegrass (Frontiers in plant science · 2021Article
- Effects of Exogenous Abscisic Acid (ABA) on Carotenoids and Petal Color inPlants (Basel, Switzerland) · 2020Article
- Food Legumes and Rising Temperatures: Effects, Adaptive Functional Mechanisms Specific to Reproductive Growth Stage and Strategies to Improve Heat Tolerance.Frontiers in plant science · 2017Review
- Breeding for plant heat tolerance at vegetative and reproductive stages.Plant reproduction · 2016Review
- DELAY OF GERMINATION1 (DOG1) regulates both seed dormancy and flowering time through microRNA pathways.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Genetic Variation for Thermotolerance in Lettuce Seed Germination Is Associated with Temperature-Sensitive Regulation of ETHYLENE RESPONSE FACTOR1 (ERF1).Plant physiology · 2016Article
- Abscisic acid (ABA) regulates grape bud dormancy, and dormancy release stimuli may act through modification of ABA metabolism.Journal of experimental botany · 2015Article
- Phenotypic analysis of the Arabidopsis heat stress response during germination and early seedling development.Plant methods · 2014Article
- Seed dormancy and germination-emerging mechanisms and new hypotheses.Frontiers in plant science · 2014Review
- An Ultra-High-Density, Transcript-Based, Genetic Map of Lettuce.G3 (Bethesda, Md.) · 2013Article
- Expression of 9-cis-EPOXYCAROTENOID DIOXYGENASE4 is essential for thermoinhibition of lettuce seed germination but not for seed development or stress tolerance.The Plant cell · 2013Article
- Plant tolerance to high temperature in a changing environment: scientific fundamentals and production of heat stress-tolerant crops.Frontiers in plant science · 2013Article
- ABA crosstalk with ethylene and nitric oxide in seed dormancy and germination.Frontiers in plant science · 2013Article
- Beyond gibberellins and abscisic acid: how ethylene and jasmonates control seed germination.Plant cell reports · 2012Review
- Induction of dormancy in Arabidopsis summer annuals requires parallel regulation of DOG1 and hormone metabolism by low temperature and CBF transcription factors.The Plant cell · 2011Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thermoinhibition, or failure of seeds to germinate when imbibed at warm temperatures, can be a significant problem in lettuce (Lactuca sativa L.) production. The reliability of stand establishment would be improved by increasing the ability of lettuce seeds to germinate at high temperatures. Genes encoding germination- or dormancy-related proteins were mapped in a recombinant inbred line population derived from a cross between L. sativa cv. Salinas and L. serriola accession UC96US23. This revealed several candidate genes that are located in the genomic regions containing quantitative trait loci (QTLs) associated with temperature and light requirements for germination. In particular, LsNCED4, a temperature-regulated gene in the biosynthetic pathway for abscisic acid (ABA), a germination inhibitor, mapped to the center of a previously detected QTL for high temperature germination (Htg6.1) from UC96US23. Three sets of sister BC(3)S(2) near-isogenic lines (NILs) that were homozygous for the UC96US23 allele of LsNCED4 at Htg6.1 were developed by backcrossing to cv. Salinas and marker-assisted selection followed by selfing. The maximum temperature for germination of NIL seed lots with the UC96US23 allele at LsNCED4 was increased by 2-3°C when compared with sister NIL seed lots lacking the introgression. In addition, the expression of LsNCED4 was two- to threefold lower in the former NIL lines as compared to expression in the latter. Together, these data strongly implicate LsNCED4 as the candidate gene responsible for the Htg6.1 phenotype and indicate that decreased ABA biosynthesis at high imbibition temperatures is a major factor responsible for the increased germination thermotolerance of UC96US23 seeds.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.