Trial reportEuropean journal of applied physiology2010
Inter-individual variability in the adaptation of human muscle specific tension to progressive resistance training.
Trial report in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Task Specificity of Dynamic Resistance Training and Its Transferability to Non-trained Isometric Muscle Strength: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Specific tension of human muscle in vivo: a systematic review.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Pooled it
- Heavy resistance exercise training in older men: A responder and inter-individual variability analysis.PloS one · 2026Trial
- Repeated Resistance Training Reveals the Reproducibility of Muscle Strength and Size Responses Within Individuals.European journal of sport science · 2025Trial
- Is Exercise During Androgen Deprivation Therapy Effective and Safe? A Randomized Controlled Trial.Scandinavian journal of medicine & science in sports · 2025Trial
- Hydrolysed Collagen Supplementation Enhances Patellar Tendon Adaptations to 12 Weeks' Resistance Training in Middle-Aged Men.European journal of sport science · 2025Trial
- Variability in resistance training trajectories of breast cancer patients undergoing therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training.Acta physiologica (Oxford, England) · 2023Trial
- Muscles adaptation to aging and training: architectural changes - a randomised trial.BMC geriatrics · 2021Trial
- The effect of Nordic hamstring strength training on muscle architecture, stiffness, and strength.European journal of applied physiology · 2017Trial
- Heterogeneity in resistance training-induced muscle strength and mass responses in men and women of different ages.Age (Dordrecht, Netherlands) · 2016Trial
- Heterogeneity of physical function responses to exercise training in older adults.Journal of the American Geriatrics Society · 2015Trial
- Increase in vastus lateralis aponeurosis width induced by resistance training: implications for a hypertrophic model of pennate muscle.European journal of applied physiology · 2015Trial
- Analytical approaches to account for muscle size when evaluating strength.European journal of applied physiology · 2026Review
- Isometric training at longer muscle-tendon complex lengths: A potential countermeasure to impaired neuro-muscle-tendon function during space travel.Experimental physiology · 2026Review
- Estimating Muscle Parameters via Hierarchical Bayesian Neuromechanics.bioRxiv : the preprint server for biology · 2026Article
- Muscle Growth Is Very Strongly Correlated with Strength Gains after Lower Body Resistance Training: New Insight from Within-Participant Associations.Medicine and science in sports and exercise · 2025Article
- Effects of a daily, home-based, 5-minute eccentric exercise program on physical fitness, body composition, and health in sedentary individuals.European journal of applied physiology · 2025Article
- Genetic prediction of lower limb isometric strength changes after 12 weeks of resistance training.Biology of sport · 2025Article
- Impact of resistance and high-intensity interval training on body composition, physical function, and temporal dynamics of adaptation in older women with impaired cardiometabolic health: a randomized clinical trial.BMC sports science, medicine & rehabilitation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Considerable variation exists between people in the muscle response to resistance training, but there are numerous ways muscle might adapt to overload that might explain this variable response. Therefore, the aim of this study was to quantify the range of responses concerning the training-induced change in maximum voluntary contraction (MVC) knee joint torque, quadriceps femoris (QF) maximum muscle force (F), physiological cross-sectional area (PCSA) and specific tension (F/PCSA). It was hypothesized that the variable change in QF specific tension between individuals would be less than that of MVC. Fifty-three untrained young men performed progressive leg-extension training three times a week for 9 weeks. F was determined from MVC torque, voluntary muscle activation level, antagonist muscle co-activation and patellar tendon moment arm. QF specific tension was established by dividing F by QF PCSA, which was calculated from the ratio of QF muscle volume to muscle fascicle length. MVC torque increased by 26 ± 11% (P < 0.0001; range -1 to 52%), while F increased by 22 ± 11% (P < 0.0001; range -1 to 44%). PCSA increased by 6 ± 4% (P < 0.001; range -3 to 18%) and specific tension increased by 17 ± 11% (P < 0.0001; range -5 to 39%). In conclusion, training-induced changes in F and PCSA varied substantially between individuals, giving rise to greater inter-individual variability in the specific tension response compared to that of MVC. Furthermore, it appears that the change in specific tension is responsible for the variable change in MVC.
Indexed as
Identifiers
20703498What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.