Evidence map›Paper›PMID 20703450›Full record

ArticlePsychopharmacology2010

Relapse to smoking during unaided cessation: clinical, cognitive and motivational predictors.

Jane Powell, Lynne Dawkins, Robert West, John Powell, Alan Pickering

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Psychopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 99 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Possible New Symptoms of Tobacco Withdrawal II: Anhedonia-A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
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  7. A systematic review of the relationships between craving and smoking cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013
    Pooled it
  8. The clinical significance of drug craving.Annals of the New York Academy of Sciences · 2012
    Pooled it
  9. Trial
  10. Do lab-based assessments of pretreatment smoking reinforcement and cue-specific craving predict smoking cessation with varenicline?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
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  16. Effect of attentional retraining on cognition, craving, and smoking in African American smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

5 authors.

Jane PowellDepartment of Psychology, Goldsmiths University of London, Lewisham Way, New Cross, London, SE14 6NW, UK. j.powell@gold.ac.uk
Lynne Dawkins
Robert West
John Powell
Alan Pickering

Funding

PHS HHS NIDA 3527427
6 · The paper itself

Abstract

rationaleNeurobiological models of addiction suggest that abnormalities of brain reward circuitry distort salience attribution and inhibitory control processes, which in turn contribute to high relapse rates.

objectivesThe aim of this study is to determine whether impairments of salience attribution and inhibitory control predict relapse in a pharmacologically unaided attempt at smoking cessation.

methodsOne hundred forty one smokers were assessed on indices of nicotine consumption/dependence (e.g. The Fagerström Test of Nicotine Dependence, cigarettes per day, salivary cotinine) and three trait impulsivity measures. After overnight abstinence, they completed experimental tests of cue reactivity, attentional bias to smoking cues, response to financial reward, motor impulsiveness and response inhibition (antisaccades). They then started a quit attempt with follow-up after 7 days, 1 month and 3 months; abstinence was verified via salivary cotinine levels ≤20 ng/ml.

resultsRelapse rates at each point were 52.5%, 64% and 76.3%. The strongest predictor was pre-cessation salivary cotinine; other smoking/dependence indices did not explain additional outcome variance and neither did trait impulsivity. All experimental indices except responsivity to financial reward significantly predicted a 1-week outcome. Salivary cotinine, attentional bias to smoking cues and antisaccade errors explained unique as well as shared variance. At 1 and 3 months, salivary cotinine, motor impulsiveness and cue reactivity were all individually predictive; the effects of salivary cotinine and motor impulsiveness were additive.

conclusionsThese data provide some support for the involvement of abnormal cognitive and motivational processes in sustaining smoking dependence and suggest that they might be a focus of interventions, especially in the early stages of cessation.

Indexed as

Behavior, AddictiveCognitionMotivationSmoking PreventionAdolescentAdultAgedAttentionChi-Square DistributionCuesDouble-Blind MethodEnglandFemaleHumansImpulsive BehaviorInhibition, Psychological

Identifiers

PMID20703450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.