ArticleBiology of reproduction2010
Aberrant growth and pattern formation in Peromyscus hybrid placental development.
Article in Biology of reproduction, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Craniomandibular form and body size variation of first generation mouse hybrids: A model for hominin hybridization.Journal of human evolution · 2018Article
- In vitro culture of ovarian follicles from Peromyscus.Seminars in cell & developmental biology · 2017Review
- Peromyscus transcriptomics: Understanding adaptation and gene expression plasticity within and between species of deer mice.Seminars in cell & developmental biology · 2017Review
- Genomic imprinting, disrupted placental expression, and speciation.Evolution; international journal of organic evolution · 2016Article
- Biased Allele Expression and Aggression in Hybrid Honeybees may be Influenced by Inappropriate Nuclear-Cytoplasmic Signaling.Frontiers in genetics · 2015Article
- Parent-of-origin growth effects and the evolution of hybrid inviability in dwarf hamsters.Evolution; international journal of organic evolution · 2014Article
- Imprinted gene expression in hybrids: perturbed mechanisms and evolutionary implications.Heredity · 2014Review
- A genetic map of Peromyscus with chromosomal assignment of linkage groups (a Peromyscus genetic map).Mammalian genome : official journal of the International Mammalian Genome Society · 2014Article
- In vitro culture of early secondary preantral follicles in hanging drop of ovarian cell-conditioned medium to obtain MII oocytes from outbred deer mice.Tissue engineering. Part A · 2013Article
- Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth.Developmental biology · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Crosses between the North American deer mouse species Peromyscus maniculatus (BW) and P. polionotus (PO) produce dramatic asymmetric developmental effects. BW females mated to PO males (female bw × male po) produce viable growth-retarded offspring. In contrast, PO females mated to BW males (female PO × male BW) produce overgrown but dysmorphic conceptuses. Most female PO × male BW offspring are dead by midgestation; those surviving to later time points display numerous defects reminiscent of several diseases. The hybrid effects are particularly pronounced in the placenta. Here we examine placental morphological defects via histology and in situ hybridization as well as the relationship between growth and mortality in the female PO × male BW cross. These assays indicate altered hybrid fetal:placental ratios by the equivalent of mouse (Mus) Embryonic Day (E) 13 and disorganization and labyrinth defects in female PO × male BW placentas and confirm earlier suggestions of a severely reduced junctional zone in the female bw × male po hybrids. Further, we show that both cellular proliferation and death are abnormal in the hybrids through BrdU incorporation and TUNEL assays, respectively. Together the data indicate that the origin of the effects is prior to the equivalent of Mus E10. Finally, as the majority of these assays had not previously been performed on Peromyscus, these studies provide comparative data on wild-type placentation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.