Evidence map›Paper›PMID 20702621›Full record

ArticleJournal of virology2010

Structure of Penaeus stylirostris densovirus, a shrimp pathogen.

Bärbel Kaufmann, Valorie D Bowman, Yi Li, Jozsef Szelei, Peter J Waddell, Peter Tijssen, Michael G Rossmann

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

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  12. Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Article
  14. Viruses · 2019
    Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Bärbel KaufmannDepartment of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, IN 47907-2054, USA.
Valorie D Bowman
Yi Li
Jozsef Szelei
Peter J Waddell
Peter Tijssen
Michael G Rossmann
State Street (United States) · USInstitut National de la Recherche Scientifique · CA

Funding

XRAY CRYSTALLOGRAPHIC STRUCTURE ANALYSIS: PROTEIN SORTINGP41RR001081 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GODDARD, THOMAS · 1985 to 2011
$17.6M
STRUCTURE OF A SMALL SPHERICAL VIRUSR37AI011219 · NIAID · PURDUE UNIVERSITY WEST LAFAYETTE · PI ROSSMANN, MICHAEL G · 1986 to 2015
$6.6M
STRUCTURE OF A SMALL SPHERICAL VIRUSR01AI011219 · NIAID · PURDUE UNIVERSITY WEST LAFAYETTE · PI KUHN, RICHARD J. · 1985 to 2020
$2.4M
PARVOVIRUS STRUCTURE, CAPSID ASSEMBLY, AND RECEPTORSR01AI033468 · NIAID · CORNELL UNIVERSITY ITHACA · PI PARRISH, COLIN R. · 1993 to 2007
$2.3M
Comparative Bioinformatics and TP53 ExpressionR01LM008626 · NLM · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI WADDELL, PETER J · 2005 to 2009
$1.5M
NCI NIH HHS Y1-CO-1020NCRR NIH HHS P41 RR001081NCRR NIH HHS P41 RR-01081NIAID NIH HHS AI 11219NIAID NIH HHS AI 33468NIAID NIH HHS R01 AI011219NIAID NIH HHS R01 AI033468NIAID NIH HHS R37 AI011219NIGMS NIH HHS Y1-GM-1104NLM NIH HHS 5R01LM008626NLM NIH HHS R01 LM008626
6 · The paper itself

Abstract

Penaeus stylirostris densovirus (PstDNV), a pathogen of penaeid shrimp, causes significant damage to farmed and wild shrimp populations. In contrast to other parvoviruses, PstDNV probably has only one type of capsid protein that lacks the phospholipase A2 activity that has been implicated as a requirement during parvoviral host cell infection. The structure of recombinant virus-like particles, composed of 60 copies of the 37.5-kDa coat protein, the smallest parvoviral capsid protein reported thus far, was determined to 2.5-Å resolution by X-ray crystallography. The structure represents the first near-atomic resolution structure within the genus Brevidensovirus. The capsid protein has a β-barrel "jelly roll" motif similar to that found in many icosahedral viruses, including other parvoviruses. The N-terminal portion of the PstDNV coat protein adopts a "domain-swapped" conformation relative to its twofold-related neighbor similar to the insect parvovirus Galleria mellonella densovirus (GmDNV) but in stark contrast to vertebrate parvoviruses. However, most of the surface loops have little structural resemblance to any of the known parvoviral capsid proteins.

Indexed as

AnimalsCapsid ProteinsCrystallography, X-RayDensovirusPenaeidaeProtein ConformationCapsid Proteins

Identifiers

PMID20702621
PMCPMC2953158
OpenAlexW2008061273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.