ArticleProceedings. Biological sciences2011
Host plant quality, selection history and trade-offs shape the immune responses of Manduca sexta.
Article in Proceedings. Biological sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- The role of a viral symbiont in the thermal mismatch of host-parasitoid interactions.The Journal of experimental biology · 2026Article
- Muscling in on immunity: the role of muscle in the insect immune response, demonstrating the value of a whole organism perspective.Frontiers in immunology · 2026Review
- Article
- High Quality Diet Enhances Immune Response and Affects Gene Expression During Viral Infection in an Insect Herbivore.Molecular ecology · 2025Article
- Immune function of the serosa in hemimetabolous insect eggs.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Use of an exotic host plant shifts immunity, chemical defense, and viral burden in wild populations of a specialist insect herbivore.Ecology and evolution · 2022Article
- The benefits of being dominant: health correlates of male social rank and age in a marmot.Current zoology · 2022Article
- Article
- Growth, stress, and acclimation responses to fluctuating temperatures in field and domesticated populations ofEcology and evolution · 2020Article
- Polyphenol-Rich Purple Corn Pericarp Extract Adversely Impacts Herbivore Growth and Development.Insects · 2020Article
- The nutritional landscape of host plants for a specialist insect herbivore.Ecology and evolution · 2019Article
- Genotypic variation in parasite avoidance behaviour and other mechanistic, nonlinear components of transmission.Proceedings. Biological sciences · 2019Article
- Host plant-dependent effects of microbes and phytochemistry on the insect immune response.Oecologia · 2019Article
- Across Multiple Species, Phytochemical Diversity and Herbivore Diet Breadth Have Cascading Effects on Herbivore Immunity and Parasitism in a Tropical Model System.Frontiers in plant science · 2018Article
- Socioecological predictors of immune defences in wild spotted hyenas.Functional ecology · 2016Article
- Immune benefits from alternative host plants could maintain polyphagy in a phytophagous insect.Oecologia · 2015Article
- Egg survival is reduced by grave-soil microbes in the carrion beetle, Nicrophorus vespilloides.BMC evolutionary biology · 2014Article
- Reduced plant nutrition under elevated CO₂ depresses the immunocompetence of cotton bollworm against its endoparasite.Scientific reports · 2014Article
- Can caterpillar density or host-plant quality explain host-plant-related parasitism of a generalist forest caterpillar assemblage?Oecologia · 2013Observational
- Influences of Plant Traits on Immune Responses of Specialist and Generalist Herbivores.Insects · 2012Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune defences are an important component of fitness. Yet susceptibility to pathogens is common, suggesting the presence of ecological and evolutionary limitations on immune defences. Here, we use structural equation modelling to quantify the direct effects of resource quality and selection history, and their indirect effects mediated via body condition prior to an immune challenge on encapsulation and melanization immune defences in the tobacco hornworm, Manduca sexta. We also investigate allocation trade-offs among immune defences and growth rate following an immune challenge. We found considerable variation in the magnitude and direction of the direct effects of resource quality and selection history on immune defences and their indirect effects mediated via body condition and allocation trade-offs. Greater resource quality and evolutionary exposure to pathogens had positive direct effects on encapsulation and melanization. The indirect effect of resource quality on encapsulation mediated via body condition was substantial, whereas indirect effects on melanization were negligible. Individuals in better condition prior to the immune challenge had greater encapsulation; however, following the immune challenge, greater encapsulation traded off with slower growth rate. Our study demonstrates the importance of experimentally and analytically disentangling the relative contributions of direct and indirect effects to understand variation in immune defences.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.