Trial reportEuropean journal of applied physiology2010
Skin blood flow differentially affects near-infrared spectroscopy-derived measures of muscle oxygen saturation and blood volume at rest and during dynamic leg exercise.
Trial report in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 80 citations in OpenAlex.
- A heat and moisture-exchanging mask impairs self-paced maximal running performance in a sub-zero environment.European journal of applied physiology · 2021Trial
- Land vs. water HIIE effects on muscle oxygenation and physiological parameter responses in postmenopausal women.Scientific reports · 2020Trial
- Near-Infrared Spatially Resolved Spectroscopy as an Indirect Technique to Assess Brown Adipose Tissue in Young Women.Molecular imaging and biology · 2019Trial
- Influence of heat stress and exercise intensity on vastus lateralis muscle and prefrontal cortex oxygenation.European journal of applied physiology · 2013Trial
- Influence of priming exercise on muscle deoxy[Hb + Mb] during ramp cycle exercise.European journal of applied physiology · 2012Trial
- Distinguishing Muscle Oxygen Saturation from Tissue Oxygen Saturation: Accuracy, Limitations, and Practical Utility in Muscle Oximetry.Sports medicine - open · 2026Article
- Exploration of the associations between muscle oxygen saturation and skin temperature responses during isokinetic strength exercise.PloS one · 2026Article
- Physiological Predictors of Peak Velocity in the VAM-EVAL Incremental Test and the Role of Kinematic Variables in Running Economy in Triathletes.Sports (Basel, Switzerland) · 2025Article
- Profiles of muscle-specific oxygenation responses and thresholds during graded cycling incremental test.European journal of applied physiology · 2025Article
- Intramuscular blood flow and muscle oxygenation of the vastus lateralis response to intermittent incremental muscle contractions.Experimental physiology · 2025Article
- Evaluation of leg symmetry in muscle oxygen saturation during submaximal to maximal cycling exercise.European journal of sport science · 2025Article
- Upper body compression wear improves muscle oxygenation following intense video game training: a randomized cross-over study among competitive gamers.BMC sports science, medicine & rehabilitation · 2023Article
- Application of blood flow restriction in hypoxic environment augments muscle deoxygenation without compromising repeated sprint exercise performance.Experimental physiology · 2023Article
- Epinephrine iontophoresis attenuates changes in skin blood flow and abolishes cutaneous contamination of near-infrared diffuse correlation spectroscopy estimations of muscle perfusion.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- Differential impact of heat and hypoxia on dynamic oxygen uptake and deoxyhemoglobin parameters during incremental exhaustive exercise.Frontiers in physiology · 2023Article
- The effect of severe intensity bouts on muscle oxygen saturation responses in trained cyclists.Frontiers in sports and active living · 2023Article
- Evidence that large vessels do affect near infrared spectroscopy.Scientific reports · 2022Article
- Impact of cutaneous blood flow on NIR-DCS measures of skeletal muscle blood flow index.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Are mode-specific differences in performance fatigability attributable to muscle oxygenation?European journal of applied physiology · 2021Article
- Spectral Analysis of Muscle Hemodynamic Responses in Post-Exercise Recovery Based on Near-Infrared Spectroscopy.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of skin blood flow changes on near-infrared spectroscopy (NIRS)-derived measures of muscle oxygen saturation (SmO(2)) and blood volume has not been fully established. We measured SmO(2) and total hemoglobin concentration ([tHb]) responses of the right vastus lateralis during rest and dynamic knee extension exercise in ten young, healthy males. The protocol was repeated four times: twice without thigh heating for reliability, and twice with different grades of thigh heating for assessing the impact of cutaneous vasodilation on SmO(2) and Δ[tHb]. The reliability of our SmO(2) and [tHb] measurements was good. Thigh heating at 37 and 42°C caused marked increases in cutaneous vascular conductance (CVC) during rest and exercise (P < 0.001 between each condition), and small increases in SmO(2) during rest (from 69 ± 8% to 71 ± 7% and 73 ± 6%, respectively; P < 0.05 between each condition), but not during exercise (e.g. 1 min exercise: 51 ± 11% vs. 51 ± 11% and 52 ± 11%, respectively; P > 0.05 at all time points). In contrast, heating-induced increases in %CVC(peak) were accompanied by increases in [tHb] at rest and during exercise and a decrease in Δ[tHb] during exercise (all P < 0.05). Our findings suggest that NIRS-derived measures of SmO(2) and blood volume are differentially affected by skin blood flow at rest and during exercise. The findings from this study should be considered in NIRS experiments where skin blood flow can change markedly (e.g. high-intensity and/or prolonged exercise).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.