Evidence map›Paper›PMID 20700119›Full record

ArticleBritish journal of cancer2010

Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey.

Z He, Y Zhao, C Guo, Y Liu, M Sun, F Liu, X Wang, F Guo, K Chen, L Gao and 8 more

Abstract read
In one paragraph

Article in British journal of cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Esophageal cancer: from pathogenesis to precision therapies.Signal transduction and targeted therapy · 2026
    Review
  6. Article
  7. Changes in Geographic Variation and Socioeconomic Inequalities in Esophageal Cancer Mortality in China, 1973-2017.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Esophageal cancer: Epidemiology, risk factors and screening.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Diet, nutrition, and cancer: past, present and future.Nature reviews. Clinical oncology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Z HeKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Laboratory of Genetics, Peking University School of Oncology, Beijing Cancer Hospital & Institute, 52 Fucheng Rd. Hai Dian District, 100142 Beijing, People's Republic of China.
Y Zhao
C Guo
Y Liu
M Sun
F Liu
X Wang
F Guo
K Chen
L Gao
T Ning
Y Pan
Y Li
S Zhang
C Lu
Z Wang
H Cai
Y Ke

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe etiology of esophageal squamous cell cancer (ESCC) in high prevalence regions of China remains unclear.

methodsEndoscopic biopsies were conducted among 7381 inhabitants aged from 25 to 65 of Anyang, China.

resultsIn this study, 2.57, 0.20 and 0.16% of the participants had mild, moderate and severe squamous dysplasia, respectively; 0.19 and 0.08% showed squamous carcinoma in situ and invasive ESCC. Using deep well (depth >100 meters) as water source (odds ratio=0.72, 95% confidence interval: 0.54-0.96) was negatively associated with ESCC and its precursors, whereas tobacco and alcohol use were not significantly associated with ESCC.

conclusionsWater source and other factors in this region need further evaluation by longitudinal studies.

Indexed as

AdultAgedAlcohol DrinkingCarcinoma, Squamous CellChinaEsophageal NeoplasmsEsophagoscopyEsophagusFemaleHumansMaleMiddle AgedPrecancerous ConditionsPrevalenceRisk FactorsSmoking

Identifiers

PMID20700119
PMCPMC2965859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.