ArticlePlant physiology2010
The glabra1 mutation affects cuticle formation and plant responses to microbes.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 106 citations in OpenAlex.
- Transcriptional control of cuticle formation during development.Journal of experimental botany · 2026Review
- MYB Transcription Factors Negatively RegulatePlants (Basel, Switzerland) · 2026Article
- The sleeping giant needs coffee: Overlooked areas for integrating plant ecophysiology and evolutionary biology.American journal of botany · 2026Review
- Silica nanoparticles suppress fungal pathogenic allies to alleviate Astragalus root rot.Microbiome · 2025Article
- Identification and expression profiling of theFrontiers in plant science · 2025Article
- Mechanosensation in leaf veins.Science advances · 2023Article
- Mechanodetection of neighbor plants elicits adaptive leaf movements through calcium dynamics.Nature communications · 2023Article
- Regulation of Salicylic Acid and N-Hydroxy-Pipecolic Acid in Systemic Acquired Resistance.The plant pathology journal · 2023Review
- Lipid transfer proteins involved in plant-pathogen interactions and their molecular mechanisms.Molecular plant pathology · 2022Review
- Genome-Wide Characterization and Expression Analysis of GeBP Family Genes in Soybean.Plants (Basel, Switzerland) · 2022Article
- Mechanosensory trichome cells evoke a mechanical stimuli-induced immune response in Arabidopsis thaliana.Nature communications · 2022Article
- Silver Nanoparticles Alter Microtubule Arrangement, Dynamics and Stress Phytohormone Levels.Plants (Basel, Switzerland) · 2022Article
- Identification and characterization of a novel gene involved in glandular trichome development inFrontiers in plant science · 2022Article
- Speaking the language of lipids: the cross-talk between plants and pathogens in defence and disease.Cellular and molecular life sciences : CMLS · 2021Review
- Genome-wide QTL analysis of tomato fruit cuticle deposition and composition.Horticulture research · 2021Article
- Review
- Article
- Deciphering the Novel Role of AtMIN7 in Cuticle Formation and Defense against the Bacterial Pathogen Infection.International journal of molecular sciences · 2020Article
- The plant cuticle regulates apoplastic transport of salicylic acid during systemic acquired resistance.Science advances · 2020Article
- Lipidomic and transcriptomic analysis reveals reallocation of carbon flux from cuticular wax into plastid membrane lipids in a glossy "Newhall" navel orange mutant.Horticulture research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic acquired resistance (SAR) is a form of defense that provides resistance against a broad spectrum of pathogens in plants. Previous work indicates a role for plastidial glycerolipid biosynthesis in SAR. Specifically, mutations in FATTY ACID DESATURASE7 (FAD7), which lead to reduced trienoic fatty acid levels and compromised plastidial lipid biosynthesis, have been associated with defective SAR. We show that the defective SAR in Arabidopsis (Arabidopsis thaliana) fad7-1 plants is not associated with a mutation in FAD7 but rather with a second-site mutation in GLABRA1 (GL1), a gene well known for its role in trichome formation. The compromised SAR in gl1 plants is associated with impairment in their cuticles. Furthermore, mutations in two other components of trichome development, GL3 and TRANSPARENT TESTA GLABRA1, also impaired cuticle development and SAR. This suggests an overlap in the biochemical pathways leading to cuticle and trichome development. Interestingly, exogenous application of gibberellic acid (GA) not only enhanced SAR in wild-type plants but also restored SAR in gl1 plants. In contrast to GA, the defense phytohoromes salicylic acid and jasmonic acid were unable to restore SAR in gl1 plants. GA application increased levels of cuticular components but not trichome formation on gl1 plants, thus implicating cuticle, but not trichomes, as an important component of SAR. Our findings question the prudence of using mutant backgrounds for genetic screens and underscore a need to reevaluate phenotypes previously studied in the gl1 background.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.