Evidence map›Paper›PMID 20699206›Full record

ArticleIEEE transactions on bio-medical engineering2011

A macro finite-element formulation for cardiac electrophysiology simulations using hybrid unstructured grids.

Bernardo M Rocha, Ferdinand Kickinger, Anton J Prassl, Gundolf Haase, Edward J Vigmond, Rodrigo Weber dos Santos, Sabine Zaglmayr, Gernot Plank

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Toward GPGPU accelerated human electromechanical cardiac simulations.International journal for numerical methods in biomedical engineering · 2014
    Article
  10. Modeling the dispersion in electromechanically coupled myocardium.International journal for numerical methods in biomedical engineering · 2013
    Article
  11. Article
  12. Article
  13. Computational approaches to understand cardiac electrophysiology and arrhythmias.American journal of physiology. Heart and circulatory physiology · 2012
    Review
  14. Article
  15. Accelerating cardiac bidomain simulations using graphics processing units.IEEE transactions on bio-medical engineering · 2012
    Article
  16. Modeling defibrillation of the heart: approaches and insights.IEEE reviews in biomedical engineering · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bernardo M RochaInstitute of Biophysics, Medical University of Graz, Graz 8010, Austria. bernardosk@gmail.com
Ferdinand Kickinger
Anton J Prassl
Gundolf Haase
Edward J Vigmond
Rodrigo Weber dos Santos
Sabine Zaglmayr
Gernot Plank

Funding

Multi-scale Modeling of Calcium Mediated Triggered Activity in the HeartR01HL101196 · NHLBI · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI SHIFERAW, YOHANNES · 2010 to 2013
$1.2M
Austrian Science Fund FWF F 3210NHLBI NIH HHS R01 HL101196
6 · The paper itself

Abstract

Electrical activity in cardiac tissue can be described by the bidomain equations whose solution for large-scale simulations still remains a computational challenge. Therefore, improvements in the discrete formulation of the problem, which decrease computational and/or memory demands are highly desirable. In this study, we propose a novel technique for computing shape functions of finite elements (FEs). The technique generates macro FEs (MFEs) based on the local decomposition of elements into tetrahedral subelements with linear shape functions. Such an approach necessitates the direct use of hybrid meshes (HMs) composed of different types of elements. MFEs are compared to classic standard FEs with respect to accuracy and RAM memory usage under different scenarios of cardiac modeling, including bidomain and monodomain simulations in 2-D and 3-D for simple and complex tissue geometries. In problems with analytical solutions, MFEs displayed the same numerical accuracy of standard linear triangular and tetrahedral elements. In propagation simulations, conduction velocity and activation times agreed very well with those computed with standard FEs. However, MFEs offer a significant decrease in memory requirements. We conclude that HMs composed of MFEs are well suited for solving problems in cardiac computational electrophysiology.

Indexed as

Models, CardiovascularAction PotentialsAnimalsBody Surface Potential MappingComputer SimulationFinite Element AnalysisHeart Conduction SystemHumans

Identifiers

PMID20699206
PMCPMC3223405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.