ReviewAntioxidants & redox signaling2011
Nonhuman primate calorie restriction.
Review in Antioxidants & redox signaling, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 67 citations in OpenAlex.
- A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches.Cancers · 2025Review
- Low-input redoxomics facilitates global identification of metabolic regulators of oxidative stress in the gut.Signal transduction and targeted therapy · 2025Article
- Mass Spectrometry-Based Multiomics Identifies Metabolic Signatures of Sarcopenia in Rhesus Monkey Skeletal Muscle.Journal of proteome research · 2024Article
- Review
- Article
- The Influence of Diet on Metabolism and Health Across the Lifespan in Nonhuman Primates.Current opinion in endocrine and metabolic research · 2022Article
- The Potential of Calorie Restriction and Calorie Restriction Mimetics in Delaying Aging: Focus on Experimental Models.Nutrients · 2021Review
- Roles of interacting stress-related genes in lifespan regulation: insights for translating experimental findings to humans.Journal of translational genetics and genomics · 2021Article
- Longitudinal profiling of the blood transcriptome in an African green monkey aging model.Aging · 2020Article
- Age-Related Differences in the Gut Microbiome of Rhesus Macaques.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Low cognitive flexibility as a risk for heavy alcohol drinking in non-human primates.Alcohol (Fayetteville, N.Y.) · 2019Article
- Aging research using the common marmoset: Focus on aging interventions.Nutrition and healthy aging · 2019Article
- A Method to Investigate Astrocyte and Microglial Morphological Changes in the Aging Brain of the Rhesus Macaque.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Non-human primates as a model for aging.Biochimica et biophysica acta. Molecular basis of disease · 2018Review
- The Ultrastructure, Spatial Distribution, and Osmium Tetroxide Binding of Lipofuscin and Melanosomes in Aging Monkey Retinal Epithelium.Current eye research · 2018Article
- Sirtuins as Mediator of the Anti-Ageing Effects of Calorie Restriction in Skeletal and Cardiac Muscle.International journal of molecular sciences · 2018Review
- Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys.Cell metabolism · 2018Article
- Caloric Restriction and Healthy Life Span: Frail Phenotype of Nonhuman Primates in the Wisconsin National Primate Research Center Caloric Restriction Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Article
- Nutrition modulation of human aging: The calorie restriction paradigm.Molecular and cellular endocrinology · 2017Review
- Regulation of metabolic health and aging by nutrient-sensitive signaling pathways.Molecular and cellular endocrinology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Calorie restriction (CR) is the only dietary intervention that repeatedly extends both median and maximal lifespan in a broad range of species. Although there has been considerable interest in CR and its ability to retard aging, the mechanism has remained elusive. In contrast to studies in rodent and nonmammalian systems that are now beginning to provide mechanistic insights into how CR promotes longevity, the efficacy of CR in delaying primate aging has yet to be fully demonstrated. Here we review some of the insights from CR studies in short-lived species. We describe the advantages of using the rhesus monkey as a model for human aging and detail how CR can be successfully implemented in this species. We discuss the findings from our ongoing longitudinal study and outline the effects to date of CR on rhesus monkey health. Finally, we highlight the importance of primate studies in the context of aging research and its potential to advance our understanding of human aging and health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.