ArticleWorld journal of gastroenterology2010
Helicobacter pylori infection concomitant with metabolic syndrome further increase risk of colorectal adenomas.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Burden of gastric cancer attributable to Helicobacter pylori in 27 countries from seven geographic regions in 2022.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Pooled it
- Association between Helicobacter pylori infection and the risk of colorectal cancer: A systematic review and meta-analysis.Medicine · 2020Pooled it
- Helicobacter pylori infection increases the risk of colorectal adenomas: cross-sectional study and meta-analysis.Digestive diseases and sciences · 2012Pooled it
- Beyond the Stomach: Exploring the Role ofExpert reviews in molecular medicine · 2026Review
- Potential Pathogens Associated with Colorectal Cancer.Current pharmaceutical biotechnology · 2025Review
- Beyond the stomach: the association betweenFrontiers in cellular and infection microbiology · 2025Review
- Relationship betweenWorld journal of gastrointestinal surgery · 2024Article
- Effects ofFrontiers in cellular and infection microbiology · 2024Review
- Helicobacter pylori and colorectal cancer-A bacterium going abroad?PLoS pathogens · 2019Article
- Correlation between Colon Polyps and Metabolic Syndrome and HP Infection Status.Gastroenterology research and practice · 2019Article
- Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori.Scientific reports · 2018Article
- Correlation betweenGastroenterology research and practice · 2018Article
- Host pathogen interactions inWorld journal of gastroenterology · 2017Review
- Clinical study of anesthetization by dezocine combined with propofol for indolent colonoscopy.World journal of gastroenterology · 2016Observational
- Helicobacter pylori and colorectal neoplasia: Is there a causal link?World journal of gastroenterology · 2016Review
- Helicobacter pylori infection: new pathogenetic and clinical aspects.World journal of gastroenterology · 2014Review
- Helicobacter pylori-related chronic gastritis as a risk factor for colonic neoplasms.World journal of gastroenterology · 2014Review
- Serum adiponectin level in diabetic patients with and without Helicobacter pylori infection: is there any difference?TheScientificWorldJournal · 2014Article
- Helicobacter pylori infection and colorectal carcinoma: is there a causal association?Journal of gastrointestinal oncology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the association of colorectal adenomas with both Helicobacter pylori (H. pylori) infection and metabolic syndrome.
methodsUsing a cross-sectional hospital-based study, we analyzed physical examination data from 9311 healthy subjects with overnight physical examinations performed between January 2004 and December 2006. Examined data included gender, age, life style, anthropometric measurements, blood pressure, biochemical and hematological studies, H. pylori infection detected by esophagogastroduodenoscopy and biopsy urease tests, and colorectal adenomas detected with a complete total colonoscopy.
resultsThe prevalence values for H. pylori infection, metabolic syndrome, and colorectal adenoma were 39.2%, 18.7%, and 20.7%, respectively. Colorectal adenoma risk factors included male gender [odd ratio (OR): 2.005, 95% confidence interval (CI): 1.740-2.310, P < 0.001], advanced age (OR: 1.046, 95% CI: 1.040-1.052, P < 0.001), smoking (OR: 1.377, 95% CI: 1.146-1.654, P = 0.001), increased body fat (OR: 1.016, 95% CI: 1.007-1.026, P = 0.001), higher white blood cell count (OR: 1.038, 95% CI: 1.005-1.073, P = 0.025), H. pylori infection (OR: 1.366, 95% CI: 1.230-1.517, P < 0.001), and metabolic syndrome (OR: 1.408, 95% CI: 1.231-1.610, P < 0.001). In addition, concomitant H. pylori infection with metabolic syndrome further increased the probability of colorectal adenomas.
conclusionOur study revealed H. pylori infection with concomitant metabolic syndrome might further increase the risk of colorectal adenomas.
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Registered trials
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