Evidence map›Paper›PMID 20698040›Full record

ReviewWorld journal of gastroenterology2010

Endoscopic treatment of Barrett's esophagus: From metaplasia to intramucosal carcinoma.

Jennifer Chennat, Irving Waxman

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Neoadjuvant and adjuvant therapy in esophageal cancer.Journal of gastrointestinal oncology · 2023
    Review
  2. Endoscopic Management of Barrett Esophagus.Gastroenterology & hepatology · 2018
    Article
  3. Article
  4. Current management of esophageal cancer.Journal of thoracic disease · 2014
    Review
  5. Review
  6. Management controversies in Barrett's oesophagus.Journal of gastroenterology · 2014
    Review
  7. Review
  8. Article
  9. Gastroesophageal reflux disease: From heartburn to cancer.World journal of gastroenterology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer ChennatCenter for Endoscopic Research and Therapeutics, Section of Gastroenterology, Department of Medicine, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, United States.
Irving Waxman
University of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The annual incidence of adenocarcinoma arising from Barrett's esophagus (BE) is approximately 0.5%. Through a process of gradual transformation from low-grade dysplasia to high-grade dysplasia (HGD), adenocarcinoma can develop in the setting of BE. The clinical importance of appropriate identification and treatment of BE in its various stages, from intestinal metaplasia to intramucosal carcinoma (IMC) hinges on the dramatically different prognostic status between early neoplasia and more advanced stages. Once a patient has symptoms of adenocarcinoma, there is usually locally advanced disease with an approximate 5-year survival rate of about 20%. Esophagectomy has been the gold standard treatment for BE with HGD, due to the suspected risk of harboring occult invasive carcinoma, which was traditionally estimated to be as high as 40%. In recent years, the paradigm of BE early neoplasia management has recently evolved, and endoscopic therapies (endoscopic mucosal resection, radiofrequency ablation, and cryotherapy) have entered the clinical forefront as acceptable non-surgical alternatives for HGD and IMC. The goal of endoscopic therapy for HGD or IMC is to ablate all BE epithelium (both dysplastic and non-dysplastic) due to risk of synchronous/metachronous lesion development in the remaining BE segment.

Indexed as

EsophagoscopyAdenocarcinomaBarrett EsophagusCatheter AblationCryosurgeryDisease ProgressionEsophageal NeoplasmsEsophagusHumansMetaplasiaMucous MembranePhotochemotherapyPrecancerous ConditionsTreatment Outcome

Identifiers

PMID20698040
PMCPMC2921089
OpenAlexW2011279048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.