Evidence map›Paper›PMID 20697765›Full record

ArticleFunctional & integrative genomics2011

Combined meta-genomics analyses unravel candidate genes for the grain dietary fiber content in bread wheat (Triticum aestivum L.).

Umar Masood Quraishi, Florent Murat, Mickael Abrouk, Caroline Pont, Carole Confolent, François Xavier Oury, Jane Ward, Danuta Boros, Kurt Gebruers, Jan A Delcour and 9 more

Abstract read
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In one paragraph

Article in Functional & integrative genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Identification of TaqW-6AS, a novel gene controlling WE-AX content in wheat grain.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  8. Review
  9. Challenges to Increasing Dietary Fiber in White Flour and Bread.Journal of agricultural and food chemistry · 2024
    Review
  10. Article
  11. Review
  12. SyntenyViewer: a comparative genomics-driven translational research tool.Database : the journal of biological databases and curation · 2023
    Article
  13. Review
  14. Article
  15. Identification of New QTLs for Dietary Fiber Content inInternational journal of molecular sciences · 2022
    Article
  16. Article
  17. Meta-QTLs, ortho-MQTLs, and candidate genes for thermotolerance in wheat (Molecular breeding : new strategies in plant improvement · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 4 countries.

Umar Masood QuraishiINRA-University Blaise Pascal, UMR1095 Génétique, Diversité et Ecophysiologie des Céréales, 234 Avenue du Brézet, 63100, Clermont-Ferrand, France.
Florent Murat
Mickael Abrouk
Caroline Pont
Carole Confolent
François Xavier Oury
Jane Ward
Danuta Boros
Kurt Gebruers
Jan A Delcour
Christophe M Courtin
Zoltan Bedo
Luc Saulnier
Fabienne Guillon
Sandrine Balzergue
Peter R Shewry
Catherine Feuillet
Gilles Charmet
Jerome Salse
Institut National de la Recherche Agronomique · MAA-T Society · GBHungarian Academy of Sciences · HUPlant Breeding and Acclimatization Institute - National Research Institute · PL

Funding

Biotechnology and Biological Sciences Research Council BBS/E/C/00004740Biotechnology and Biological Sciences Research Council BBS/E/C/00004953Biotechnology and Biological Sciences Research Council BBS/E/C/00004976
6 · The paper itself

Abstract

Grain dietary fiber content in wheat not only affects its end use and technological properties including milling, baking and animal feed but is also of great importance for health benefits. In this study, integration of association genetics (seven detected loci on chromosomes 1B, 3A, 3D, 5B, 6B, 7A, 7B) and meta-QTL (three consensus QTL on chromosomes 1B, 3D and 6B) analyses allowed the identification of seven chromosomal regions underlying grain dietary fiber content in bread wheat. Based either on a diversity panel or on bi-parental populations, we clearly demonstrate that this trait is mainly driven by a major locus located on chromosome 1B associated with a log of p value >13 and a LOD score >8, respectively. In parallel, we identified 73 genes differentially expressed during the grain development and between genotypes with contrasting grain fiber contents. Integration of quantitative genetics and transcriptomic data allowed us to propose a short list of candidate genes that are conserved in the rice, sorghum and Brachypodium chromosome regions orthologous to the seven wheat grain fiber content QTL and that can be considered as major candidate genes for future improvement of the grain dietary fiber content in bread wheat breeding programs.

Indexed as

Dietary FiberGenomicsBiomarkersBrachypodiumBreadChromosome MappingChromosomes, PlantEdible GrainGene Expression ProfilingGenes, PlantGenotypeLinkage DisequilibriumMicrosatellite RepeatsOligonucleotide Array Sequence AnalysisOryzaPhenotypeBiomarkersDietary FiberRNA, MessengerRNA, Plant

Identifiers

PMID20697765
OpenAlexW2024499328

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.