Evidence map›Paper›PMID 20697423›Full record

ReviewNature reviews. Genetics2010

Evolution and development of shape: integrating quantitative approaches.

Christian Peter Klingenberg

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 195 papers.

0numbers the graph read from it
0cells of the map it votes in
195citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

195 citing papers in PubMed.

  1. Article
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  10. Morphological and Genetic Heterogeneity inEcology and evolution · 2025
    Article
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  16. Allometry and phylogenetic divergence: Correspondence or incongruence?Anatomical record (Hoboken, N.J. : 2007) · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

135 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Christian Peter KlingenbergFaculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK. cpk@manchester.ac.uk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morphological traits have long been a focus of evolutionary developmental biology ('evo-devo'), but new methods for quantifying shape variation are opening unprecedented possibilities for investigating the developmental basis of evolutionary change. Morphometric analyses are revealing that development mediates complex interactions between genetic and environmental factors affecting shape. Evolution results from changes in those interactions, as natural selection favours shapes that more effectively perform some fitness-related functions. Quantitative studies of shape can characterize developmental and genetic effects and discover their relative importance. They integrate evo-devo and related disciplines into a coherent understanding of evolutionary processes from populations to large-scale evolutionary radiations.

Indexed as

Biological EvolutionAnimalsDevelopmental BiologyHumansMorphogenesisSelection, Genetic

Identifiers

PMID20697423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.