Evidence map›Paper›PMID 20697365›Full record

ArticleBone marrow transplantation2011

Successful tandem (autologous-cord blood) SCT in advanced neuroblastomas with highly amplified MYCN.

K Goi, T Inukai, H Honna, K Akahane, K Hirose, I Kuroda, N Hasuda, K Koshizuka, K Takano, K Sugita

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Treatment of high-risk neuroblastoma.Korean journal of pediatrics · 2012
    Article
  7. Allogeneic stem cell transplantation for neuroblastoma.The Korean journal of hematology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

K GoiDepartment of Pediatrics, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan. kgoi@yamanashi.ac.jp
T Inukai
H Honna
K Akahane
K Hirose
I Kuroda
N Hasuda
K Koshizuka
K Takano
K Sugita
University of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although autologous tandem hematopoietic SCT has improved the prognosis of patients with advanced high-risk neuroblastoma, the results remain unsatisfactory. In an attempt to induce the graft-versus-tumor effect, we performed autologous PBSCT followed by allogeneic cord blood transplantation in three consecutive advanced neuroblastoma cases with marked BM infiltration and high MYCN amplification. Severe acute complications did not occur in any patient and they have maintained disease-free survival for 37-60 months. This strategy appears to be feasible and effective for the treatment of extremely high-risk neuroblastoma cases.

Indexed as

Bone MarrowCord Blood Stem Cell TransplantationGraft vs Tumor EffectHematopoietic Stem Cell TransplantationHumansInfantMaleNeoplasm InvasivenessNeuroblastomaN-Myc Proto-Oncogene ProteinNuclear ProteinsOncogene ProteinsPeripheral Blood Stem Cell TransplantationMYCN protein, humanN-Myc Proto-Oncogene ProteinNuclear ProteinsOncogene Proteins

Identifiers

PMID20697365
OpenAlexW2156889113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.