ArticleStructure (London, England : 1993)2010
RIG-I "sees" the 5'-triphosphate.
Article in Structure (London, England : 1993), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Negative regulators antagonizing antitumor innate immune pathways in lung cancer immune evasion.Frontiers in immunology · 2026Review
- Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.Oncotarget · 2016Article
- Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway.Trends in immunology · 2015Review
- Stabilization of human interferon-α1 mRNA by its antisense RNA.Cellular and molecular life sciences : CMLS · 2013Article
- Short double-stranded RNAs with an overhanging 5' ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoys.The Journal of biological chemistry · 2011Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
RIG-I protects host cells against various RNA viruses by sensing viral RNAs in the cytoplasm. Crystal structures of RIG-I C-terminal domain bound to 5'-triphosphate dsRNA unveils how RIG-I recognizes the 5'-triphosphate moiety, a hallmark of viral RNAs (Lu et al., 2010).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.