Evidence map›Paper›PMID 20696125›Full record

ArticleAnalytical biochemistry2010

Detection of microRNAs in dried serum blots.

Santosh Kumar Patnaik, Reema Mallick, Sai Yendamuri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical biochemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  6. Article
  7. Review
  8. Article
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  11. Review
  12. Article
  13. Review
  14. Article
  15. Biases in small RNA deep sequencing data.Nucleic acids research · 2014
    Review
  16. Review
  17. Article
  18. Review
  19. MicroRNAs in body fluids--the mix of hormones and biomarkers.Nature reviews. Clinical oncology · 2011
    Review
  20. MicroRNAs and esophageal cancer.Journal of gastrointestinal oncology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Santosh Kumar PatnaikDepartment of Thoracic Surgery, Roswell Park Cancer Institute, Buffalo, NY 14203, USA. santosh.patnaik@roswellpark.org
Reema Mallick
Sai Yendamuri

Funding

Development of a blood-based mircroRNA profile as a biomarker for lung cancerR03CA142075 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PATNAIK, SANTOSH KUMAR, REID, MARY E · 2009 to 2009
$63k
NCI NIH HHS R03 CA142075NCI NIH HHS R03CA142075-01
6 · The paper itself

Abstract

We observed the preservation of microRNAs in unrefrigerated dried serum blots. Preservation was not adversely affected by drying or storing at 37, 45, or 60°C instead of room temperature, but it was harmed when blots were dried incompletely before storage. Preservation of microRNAs in serum was not diminished if, instead of being kept frozen at -80°C, it was stored as dried blots at room temperature for 5 months or at 37°C for 4 weeks. Thus, dried blots can be a convenient and safer way to save, transport, and store serum for microRNA assays.

Indexed as

FreezingMicroRNAsPolymerase Chain ReactionTemperatureMicroRNAs

Identifiers

PMID20696125
PMCPMC2947447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.