ReviewScandinavian journal of immunology2010
Role of calcium channels in congenital heart block.
Review in Scandinavian journal of immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Autoimmune cardiac channelopathies and heart rhythm disorders: A contemporary review.Heart rhythm · 2025Review
- Anti-Ro/SSA antibodies in adult arrhythmias: pathogenesis, clinical implications, and therapeutic strategies.Frontiers in immunology · 2025Review
- Monitoring of Women with Anti-Ro/SSA and Anti-La/SSB Antibodies in Germany-Status Quo and Intensified Monitoring Concepts.Journal of clinical medicine · 2024Article
- Autoantibody:Autoantigen Competitor Decoys: Application to Cardiac Phenotypes.Frontiers in immunology · 2022Review
- Risk of QTc Interval Prolongation Associated With Circulating Anti-Ro/SSA Antibodies Among US Veterans: An Observational Cohort Study.Journal of the American Heart Association · 2021Observational
- Anti-Ro/SSA Antibodies and the Autoimmune Long-QT Syndrome.Frontiers in medicine · 2021Review
- Channelopathies of voltage-gated L-type Cav1.3/αPflugers Archiv : European journal of physiology · 2020Review
- Autoantibodies for Cardiac Channels and Sudden Cardiac Death and its Relationship to Autoimmune Disorders.Current cardiology reviews · 2019Review
- Editorial: Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease.Frontiers in cardiovascular medicine · 2019Article
- Arrhythmia and/or Cardiomyopathy Related to Maternal Autoantibodies: Descriptive Analysis of a Series of 16 Cases From a Single Center.Frontiers in pediatrics · 2019Article
- Emerging Arrhythmic Risk of Autoimmune and Inflammatory Cardiac Channelopathies.Journal of the American Heart Association · 2018Review
- Ion channelopathies of the immune system.Current opinion in immunology · 2018Review
- Autoimmunity and cardiac arrhythmias in endemic pemphigus foliaceus-Association, correlation, or causation?Heart rhythm · 2018Article
- Complete congenital heart block: A case of multilevel block.HeartRhythm case reports · 2017Article
- Assessing QT interval in patients with autoimmune chronic inflammatory diseases: perils and pitfalls.Lupus science & medicine · 2016Article
- Isolated atrioventricular block of unknown origin in the adult and autoimmunity: diagnostic and therapeutic considerations exemplified by 3 anti-Ro/SSA-associated cases.HeartRhythm case reports · 2015Article
- Long QT Syndrome: An Emerging Role for Inflammation and Immunity.Frontiers in cardiovascular medicine · 2015Review
- Calreticulin negatively regulates the surface expression of Cav1.3 L-type calcium channel.Biochemical and biophysical research communications · 2013Article
- Neonatal lupus: advances in understanding pathogenesis and identifying treatments of cardiac disease.Current opinion in rheumatology · 2012Review
- Autoantibodies and cardiac arrhythmias.Heart rhythm · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Congenital heart block (CHB) is a conduction abnormality that affects hearts of foetuses and/or newborn to mothers with autoantibodies reactive with the intracellular soluble ribonucleoproteins 48-kD La, 52-kD Ro and 60-kD Ro. CHB carries substantial mortality and morbidity, with more than 60% of affected children requiring lifelong pacemakers. Several hypotheses have been proposed to explain the pathogenesis of CHB. These can be grouped under three main hypotheses: Apoptosis, Serotoninergic and Ca channel hypothesis. Here, we discuss these hypotheses and provide recent scientific thinking that will most likely dominate the future of this field of research.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.