Evidence map›Paper›PMID 20695922›Full record

ArticleInsect molecular biology2010

Transcriptional profiling of Anopheles gambiae mosquitoes for adult age estimation.

P E Cook, S P Sinkins

Abstract read
In one paragraph

Article in Insect molecular biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Predicting the age of fieldScience advances · 2024
    Article
  4. Article
  5. Article
  6. A globalBMC bioinformatics · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. RNAi Trigger Delivery into Anopheles gambiae Pupae.Journal of visualized experiments : JoVE · 2016
    Article
  16. Article
  17. Needs for monitoring mosquito transmission of malaria in a pre-elimination world.The American journal of tropical medicine and hygiene · 2014
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P E CookDepartment of Zoology, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford, UK.
S P Sinkins

Funding

Wellcome Trust 079059
6 · The paper itself

Abstract

The age distribution of female mosquitoes in the field is a critical component of vectorial capacity because of the extrinsic incubation period of mosquito-borne pathogens. However this parameter has not been well characterized in malaria vectors because of methodological difficulties; transcriptional profiling provides a potential new approach for age determination. In Anopheles gambiae, microarrays were used to examine global gene expression over adult life. Nine genes were selected from the 2714 gene transcripts that displayed age-related transcription patterns, and quantitative reverse transcription PCR used to select the four best performing genes. The resulting age estimation assay was able to predict female age from lab-reared samples with sufficient accuracy to provide a potentially useful tool for studies of malaria epidemiology and control.

Indexed as

AgingGene Expression ProfilingGene Expression RegulationAnimalsAnophelesFemaleInsect ProteinsInsect VectorsMaleModels, BiologicalInsect Proteins

Identifiers

PMID20695922
PMCPMC2998705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.