ArticleBiomacromolecules2010
Zwitterionic chitosan derivatives for pH-sensitive stealth coating.
Article in Biomacromolecules, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Nanocapsules modify membrane interaction of polymyxin B to enable safe systemic therapy of Gram-negative sepsis.Science advances · 2021Article
- A sulfobetaine zwitterionic polymer-drug conjugate for multivalent paclitaxel and gemcitabine co-delivery.Biomaterials science · 2021Article
- Photosensitive nanocarriers for specific delivery of cargo into cells.Scientific reports · 2020Article
- Recent advances in polymeric drug delivery systems.Biomaterials research · 2020Review
- Recent advances in nanomedicine for sepsis treatment.Therapeutic delivery · 2018Review
- Small molecule delivery to solid tumors with chitosan-coated PLGA particles: A lesson learned from comparative imaging.Journal of controlled release : official journal of the Controlled Release Society · 2017Article
- Biodegradable zwitterionic sulfobetaine polymer and its conjugate with paclitaxel for sustained drug delivery.Acta biomaterialia · 2017Article
- Polyethylenimine-dermatan sulfate complex, a bioactive biomaterial with unique toxicity to CD146-positive cancer cells.ACS biomaterials science & engineering · 2017Article
- Succinylated chitosan derivative has local protective effects on intestinal inflammation.ACS biomaterials science & engineering · 2017Article
- Easy on-demand single-pass self-assembly and modification to fabricate gold@graphene-based anti-inflammatory nanoplatforms.Scientific reports · 2016Article
- Zwitterionic chitosan for the systemic treatment of sepsis.Scientific reports · 2016Article
- Photo-derived transformation from modified chitosan@calcium carbonate nanohybrids to nanosponges.Scientific reports · 2016Article
- Drug Carriers: Not an Innocent Delivery Man.The AAPS journal · 2015Review
- Dual secured nano-melittin for the safe and effective eradication of cancer cells.Journal of materials chemistry. B · 2015Article
- Design of chitosan and its water soluble derivatives-based drug carriers with polyelectrolyte complexes.Marine drugs · 2014Review
- Extracellularly activatable nanocarriers for drug delivery to tumors.Expert opinion on drug delivery · 2014Review
- Endotoxins affect diverse biological activity of chitosans in matters of hemocompatibility and cytocompatibility.Journal of materials science. Materials in medicine · 2014Article
- Tunable drug-loading capability of chitosan hydrogels with varied network architectures.Acta biomaterialia · 2014Article
- Zwitterionic chitosan-polyamidoamine dendrimer complex nanoparticles as a pH-sensitive drug carrier.Molecular pharmaceutics · 2013Article
- Application of polysaccharides for surface modification of nanomedicines.Therapeutic delivery · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Zwitterionic chitosan, a chitosan derivative with a unique pH-dependent charge profile, was employed to create a stealth coating on the cationic surface of drug carriers. Zwitterionic chitosans were synthesized by amidation of chitosan with succinic anhydride. The succinic anhydride-conjugated chitosan had an isoelectric point, which could be easily tuned from pH 4.9 to 7.1 and showed opposite charges below and above the isoelectric point. The succinic anhydride-conjugated chitosan was able to inhibit the protein adsorption to the cationic surface at physiological pH, compatible with blood components and well tolerated upon intraperitoneal injection. The succinic anhydride-conjugated chitosan has the potential to serve as a coating material to prevent protein adsorption to cationic surfaces, which can be removed in a pH-responsive manner.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.